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Gene Expression Data
Assay Details
Assay
Reference: J:86842 Norgaard GA, et al., FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development. Dev Biol. 2003 Dec 15;264(2):323-38
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6332966
Gene symbol: Nkx6-1
Gene name: NK6 homeobox 1
Antibody: anti-Nkx6-1
Results
Specimen 2A: embryonic day 14.5 (more )
Note: Triple labeled: green - Nkx6-1; blue - Ins1 (assay MGI:6332967) and Ins2 (assay MGI:6332968); red - Sst (assay MGI:6332969).
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted 2A Expression restricted to a few centrally located progenitor cells (not expressing insulin) and insulin-expressing mature beta cells
Specimen 3A: embryonic day 18.5 (more )
Note: Triple labeled: green - Nkx6-1; blue - Ins1 (assay MGI:6332967) and Ins2 (assay MGI:6332968); red - Sst (assay MGI:6332969).
Structure Level Pattern Image Note
TS26: endocrine pancreas Present Widespread 3A Expression in all cells expressing insulin.
TS26: pancreas Present Regionally restricted 3A Only a few precursor cells (not co-expressing insulin) remain, extending to stem of exocrine acini.
TS26: pancreatic duct Ambiguous 3A Authors state there was no expression in most ductal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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