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Gene Expression Data
Assay Details
Assay
Reference: J:84902 Hald J, et al., Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. Dev Biol. 2003 Aug 15;260(2):426-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6324011
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-GLU 001
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Probe/antibody name MGI:6323643 may have been used in this assay.
Results
Specimen 2A: embryonic day 12.0 (more )
Note: Double labeled: red - Glu (Gcg); green - Pdx1 (assay MGI:6324010).
Structure Level Pattern Image Note
TS20: pancreas Present 2A
Specimen 2C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: pancreas Present 2C
Specimen 3C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium dorsal bud Present Clusters 3C Expression in multiple cells clustering in dorsal bud.
TS17: pancreas primordium ventral bud Ambiguous 3C Authors state ventral bud is only commencing endocrinogenesis.
Specimen 4A: embryonic day 12.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Pdx1 (assay MGI:6324010).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Clusters 4A Expression in clusters of cells embedded within the pancreatic epithelium.
Specimen 4C: embryonic day 12.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Nkx6-1 (assay MGI:6324012).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Clusters 4C Expression in clusters of cells embedded within the pancreatic epithelium.
Specimen 4E: embryonic day 12.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Ngn3 (Neurog3 assay MGI:6324013).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Clusters 4E Expression in clusters of cells embedded within the pancreatic epithelium.
Specimen 4G: embryonic day 12.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Hes1 (assay MGI:6324014).
Structure Level Pattern Image Note
TS20: pancreas epithelium Present Clusters 4G Expression in clusters of cells embedded within the pancreatic epithelium.
Specimen 6A: embryonic day 18.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Amy (assay MGI:6324015).
Structure Level Pattern Image Note
TS26: pancreas Present 6A
Specimen 6C: embryonic day 18.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Cpa (Cpa1 assay MGI:6324016).
Structure Level Pattern Image Note
TS26: pancreas Present 6C
Specimen 6E: embryonic day 18.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Mist1 (Bhlha15 assay MGI:6324017).
Structure Level Pattern Image Note
TS26: pancreas Present 6E
Specimen 6G: embryonic day 14.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Amy (assay MGI:6324015).
Structure Level Pattern Image Note
TS22: pancreas Present 6G
Specimen 7A: embryonic day 18.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Ins1 (assay MGI:6324018 and Ins2 (assay MGI:6324023).
Structure Level Pattern Image Note
TS26: pancreas Present Regionally restricted 7A Authors report expressing cells did not coexpress insulin.
Specimen 8A: embryonic day 18.5 (more )
Note: Double labeled: red - Glu (Gcg); green - Glut2 (Slc2a2 assay MGI:6324019).
Structure Level Pattern Image Note
TS26: pancreas Present Regionally restricted 8A Expression in the periphery of the forming islets.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory