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Gene Expression Data
Assay Details
Assay
Reference: J:149237 Perez-Balaguer A, et al., Shh dependent and independent maintenance of basal midbrain. Mech Dev. 2009 May-Jun;126(5-6):301-13
Assay type: RNA in situ
MGI Accession ID: MGI:6304436
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: Otx2 probe3
Probe preparation: Antisense RNA
Results
Specimen 3A: embryonic day 10.5 (more )
Note: Double labeled: red - Otx2; blue - Pax6 (assay MGI:6304435).
Structure Level Pattern Image Note
TS17: midbrain Present 3A
TS17: brain Present Regionally restricted 3A Expression labels the rostral neural tube until the mid-hindbrain boundary.
Specimen 3B: embryonic day 10.5; Shhtm2Amc/Shhtm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. Double labeled: red - Otx2; blue - Pax6 (assay MGI:6304435).
Structure Level Pattern Image Note
TS17: midbrain Present 3B
TS17: brain Present Regionally restricted 3B Expression labels the rostral neural tube until the mid-hindbrain boundary.
Specimen 3C: embryonic day 12.5 (more )
Note: Double labeled: red - Otx2; blue - Pax6 (assay MGI:6304435).
Structure Level Pattern Image Note
TS20: midbrain Present 3C
TS20: brain Present Regionally restricted 3C Expression labels the rostral neural tube until the mid-hindbrain boundary.
Specimen 3D: embryonic day 12.5; Shhtm2Amc/Shhtm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. Double labeled: red - Otx2; blue - Pax6 (assay MGI:6304435).
Structure Level Pattern Image Note
TS20: midbrain Present 3D
TS20: brain Present Regionally restricted 3D Expression labels the rostral neural tube until the mid-hindbrain boundary.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory