Neo1tm1.1Jfcl
Targeted Allele Detail
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| Symbol: |
Neo1tm1.1Jfcl |
| Name: |
neogenin; targeted mutation 1.1, Jean-Francois Cloutier |
| MGI ID: |
MGI:6285614 |
| Synonyms: |
Neo1lox |
| Gene: |
Neo1 Location: Chr9:58781970-58943724 bp, - strand Genetic Position: Chr9, 31.81 cM
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| Alliance: |
Neo1tm1.1Jfcl page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:235517
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 1, and an frt flanked neomycin cassette and another loxP site was inserted downstream of exon 1 by homologous recombination. The neomycin cassette was removed through Flp-mediated recombination resulting in an allele with a floxable exon 1. Western blot on extracts derived from brain of homozygous animals, following Cre-mediated excision of exon 1, did not detect any protein product.
(J:235517)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Neo1 Mutation: |
63 strains or lines available
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| Original: |
J:235517 Kam JW, et al., RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
| All: |
7 reference(s) |
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Analysis Tools
