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Gene Expression Data
Assay Details
Assay
Reference: J:217512 Bessonnard S, et al., Gata6, Nanog and Erk signaling control cell fate in the inner cell mass through a tristable regulatory network. Development. 2014 Oct;141(19):3637-48
Assay type: RNA in situ
MGI Accession ID: MGI:6281420
Gene symbol: Fgf4
Gene name: fibroblast growth factor 4
Probe: Fgf4 probe35
Probe preparation: Antisense RNA
Results
Specimen 5A +/+: embryonic day 3.5 (more )
Note: Data was quantified in Fig. 5B. Triple labeled: red - Fgf4; green - Nanog (assay MGI:6281190); blue/yellow - Cdx2 (assay MGI:6281373).
Structure Level Pattern Image Note
TS4: inner cell mass Present 5A upper merge , 5A upper Fgf4 Expressed in early epiblast progenitors.
Specimen 5A +/-: embryonic day 3.5; Gata6tm2.2Sad/Gata6+ (more )
Note: Data was quantified in Fig. 5B. Triple labeled: red - Fgf4; green - Nanog (assay MGI:6281190); blue/yellow - Cdx2 (assay MGI:6281373).
Structure Level Pattern Image Note
TS4: inner cell mass Present 5A lower merge , 5A lower Fgf4 Expressed in early epiblast progenitors. The proportions of cells expressing Fgf4 were significantly higher compared with wild type.
Specimen not shown: embryonic day 3.25 (more )
Note: Data was quantified in Fig. 5C.
Structure Level Pattern Image Note
TS4: inner cell mass Present Expressed in early epiblast progenitors.
Specimen not shown: embryonic day 3.25; Gata6tm2.2Sad/Gata6+ (more )
Note: Data was quantified in Fig. 5C.
Structure Level Pattern Image Note
TS4: inner cell mass Present Expressed in early epiblast progenitors. The proportions of cells expressing Fgf4 were significantly higher compared with wild type. A precocious induction of epiblast cells was shown.
Specimen not shown: embryonic day 3.75 (more )
Note: Data was quantified in Fig. 5C.
Structure Level Pattern Image Note
TS5: inner cell mass Present Expressed in early epiblast progenitors.
Specimen not shown: embryonic day 3.75; Gata6tm2.2Sad/Gata6+ (more )
Note: Data was quantified in Fig. 5C.
Structure Level Pattern Image Note
TS5: inner cell mass Present Expressed in early epiblast progenitors. The proportions of cells expressing Fgf4 were significantly higher compared with wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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