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Gene Expression Data
Assay Details
Assay
Reference: J:171479 Hutton SR, et al., SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon. Dev Biol. 2011 Apr 1;352(1):40-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6274527
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Results
Specimen 1A/C/E/G: embryonic day 16.5 (more )
Note: Triple labeled: Sox2 is shown in red in C and E, green in G; Pax6 (assay MGI:6274528) is green in C and F; red in G; Tbr2 (Eomes; assay MGI:6274529) is green in E, blue in G.
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Strong 1A , 1G , 1C , 1E Highly expressed in ventricular zone.
TS24: telencephalon subventricular zone Weak 1E , 1A , 1C , 1G Lower levels of expression in the subventricular zone.
Specimen 1H: embryonic day 16.5 (more )
Note: Double labeled: red - Sox2; green - TuJ1 (Tubb3; assay MGI:6274530).
Structure Level Pattern Image Note
TS24: telencephalon subventricular zone Present Regionally restricted 1H Authors report Tubb3-expressing cells co-expressing Sox2 found intermittently in the ventricular zone and subventricular zone.
TS24: telencephalon ventricular layer Present Regionally restricted 1H Authors report Tubb3-expressing cells co-expressing Sox2 found intermittently in the ventricular zone and subventricular zone.
Specimen 2A: embryonic day 16.5; Sox2tm1Lpev/Sox2+ (more )
Structure Level Pattern Image Note
TS24: telencephalon subventricular zone Present 2A
TS24: telencephalon ventricular layer Present 2A
Specimen 2B inset: embryonic day 16.5; Sox2tm1Lpev/Sox2+ (more )
Note: Double labeled: red - Sox2 RNA; green - Sox2 reporter (assay MGI:6274524).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted 2B inset Authors report co-expression with Sox2 GFP reporter.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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