About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:264553 Tarchini B, et al., A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development. Dev Biol. 2018 Nov 15;443(2):153-164
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6258748
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 3B +/dwnd: embryonic day 16.5; Mctp1dwnd/Mctp1+ (more )
Note: Triple labeled: green - Sox2; red - Nr2f1 (assay MGI:6258747); blue - DAPI.
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 3B +/dwnd upper Expression in prosensory domain.

Specimen 3B dwnd/dwnd: embryonic day 16.5; Mctp1dwnd/Mctp1dwnd (more )
Note: Triple labeled: green - Sox2; red - Nr2f1 (assay MGI:6258747); blue - DAPI.
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 3B dwnd/dwnd upper Authors report expression in cochlear floor in homozygote comparable to heterozygote control.

Specimen 3C +/dwnd: embryonic day 16.5; Mctp1dwnd/Mctp1+ (more )
Note: Double labeled: green - Sox2; red - Nr2f1 (assay MGI:6258747).
Structure Level Pattern Image Note
TS24: retina Present 3C +/dwnd upper

Specimen 3C dwnd/dwnd: embryonic day 16.5; Mctp1dwnd/Mctp1dwnd (more )
Note: Double labeled: green - Sox2; red - Nr2f1 (assay MGI:6258747).
Structure Level Pattern Image Note
TS24: retina Present 3C dwnd/dwnd upper


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/28/2024
MGI 6.13
The Jackson Laboratory