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Gene Expression Data
Assay Details
Assay
Reference: J:248338 Teoh JJ, et al., BIG1 is required for the survival of deep layer neurons, neuronal polarity, and the formation of axonal tracts between the thalamus and neocortex in developing brain. PLoS One. 2017;12(4):e0175888
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6149050
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1 (I-18): sc-15607
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The authors did not specify which antibody was used, anti-Tbr1 (AB9616) MGI:6148973 may have been used.
Results
Specimen 4A ctrl E13.5: embryonic day 13.5 (more )
Note: Double labeled: green - Tbr1; red - Casp3 (assay MGI:6149049).
Structure Level Pattern Image Note
TS21: neocortex Present Regionally restricted 4A ctrl Tbr1 , 4A ctrl Max Tbr1 , 4A ctrl Max Merged , 4A ctrl Fro Tbr1 , 4A ctrl Fro Merged , 4A ctrl Merged Expression is in deep layer post-mitotic neurons.
Specimen 4A geo/geo E13.5: embryonic day 13.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Note: Double labeled: green - Tbr1; red - Casp3 (assay MGI:6149049).
Structure Level Pattern Image Note
TS21: neocortex Present Regionally restricted 4A geo/geo Tbr1 , 4A geo/geo Max Merged , 4A geo/geo Max Tbr1 , 4A geo/geo Fro Merged , 4A geo/geo Merged , 4A geo/geo Fro Tbr1 Expression is in deep layer post-mitotic neurons.
Specimen 4B ctrl E15.5: embryonic day 15.5 (more )
Note: Double labeled: green - Tbr1; red - Casp3 (assay MGI:6149049).
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted 4B ctrl Merged , 4B ctrl Fro Merged , 4B ctrl Max Merged , 4B ctrl Fro Tbr1 , 4B ctrl Max Tbr1 , 4B ctrl Tbr1 Expression is in deep layer post-mitotic neurons.
Specimen 4B geo/geo E15.5: embryonic day 15.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Note: Double labeled: green - Tbr1; red - Casp3 (assay MGI:6149049).
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted 4B geo/geo Max Merged , 4B geo/geo Fro Merged , 4B geo/geo Max Tbr1 , 4B geo/geo Merged , 4B geo/geo Fro Tbr1 , 4B geo/geo Tbr1 Expression is in deep layer post-mitotic neurons.
Specimen 4C ctrl E17.5: embryonic day 17.5 (more )
Note: Double labeled: green - Tbr1; red - Casp3 (assay MGI:6149049).
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted 4C ctrl Max Tbr1 , 4C ctrl Max Merged , 4C ctrl Tbr1 , 4C ctrl Merged Expression is in deep layer post-mitotic neurons.
Specimen 4C geo/geo E17.5: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Note: Double labeled: green - Tbr1; red - Casp3 (assay MGI:6149049).
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted 4C geo/geo Merged , 4C geo/geo Tbr1 , 4C geo/geo Max Tbr1 , 4C geo/geo Max Merged Expression is in deep layer post-mitotic neurons.
Specimen 5A top left: embryonic day 15.5 (more )
Note: Double labeled: green - Tbr1; red - Cux1 (assay MGI:6149051).
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted 5A top left Expression is in deep layer neurons.
Specimen 5A top right: embryonic day 15.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Note: Double labeled: green - Tbr1; red - Cux1 (assay MGI:6149051).
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted 5A top right Expression is in deep layer neurons.
Specimen 5A bottom left: embryonic day 17.5 (more )
Note: Double labeled: green - Tbr1; red - Cux1 (assay MGI:6149051).
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted 5A bottom left Expression is in deep layer neurons.
Specimen 5A bottom right: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Note: Double labeled: green - Tbr1; red - Cux1 (assay MGI:6149051).
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted 5A bottom right Expression is in deep layer neurons.
Specimen 5B ctrl: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted 5B ctrl Tbr1 Expression is in deep layer neurons.
Specimen 5B geo/geo: embryonic day 17.5; Arfgef1Gt(CSH465)Byg/Arfgef1Gt(CSH465)Byg (more )
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted 5B geo/geo Tbr1 Expression is in deep layer neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory