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Gene Expression Data
Assay Details
Assay
Reference: J:227089 Pirson M, et al., Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6144142
Gene symbol: Txn2
Gene name: thioredoxin 2
Antibody: anti-Trx2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Present 1E
Specimen 2N/P: embryonic day 16.5 (more )
Note: Double labeled: green - Txn2; red - Atp1b1 (assay MGI:6144143).
Structure Level Pattern Image Note
TS24: spinal cord Present Punctate 2P , 2N Authors report punctate expression and co-localization with mitochondrial marker, Atpb.
Specimen 10A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Weak Regionally restricted 10A Low expression, somewhat stronger in ventral lateral parts.
Specimen 10B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 10B More prominent ventral expression at E11.5.
Specimen 10C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Strong Regionally restricted 10C Stronger ventral expression from E13.5 to E18.5.
Specimen 10D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: spinal cord Strong Regionally restricted 10D Stronger ventral expression from E13.5 to E18.5.
Specimen 10E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Strong Regionally restricted 10E Stronger ventral expression from E13.5 to E18.5.
TS22: spinal cord white matter Strong Regionally restricted 10E Strong thread-like expression within the white matter.
Specimen 10F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Strong Regionally restricted 10F Stronger ventral expression from E13.5 to E18.5.
TS24: spinal cord white matter Strong Regionally restricted 10F Strong thread-like expression within the white matter.
Specimen 10G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: spinal cord Strong Regionally restricted 10G Stronger ventral expression from E13.5 to E18.5.
TS26: spinal cord white matter Strong Regionally restricted 10G Strong thread-like expression within the white matter.
Specimen 10H/K: embryonic day 12.5 (more )
Note: Triple labeled: green - Txn2; purple - Foxp1 (assay MGI:6144147); red - Isl1 (assay MGI:6144145) and Isl2 (assay MGI:6144251).
Structure Level Pattern Image Note
TS20: spinal cord Strong Regionally restricted 10H , 10K Authors report strong ventral expression co-localized in nucleus with motor neuron markers Isl1/2 and Foxp1.
Specimen 10L/O: embryonic day 12.5 (more )
Note: Triple labeled: green - Txn2; purple - Foxp1 (assay MGI:6144147); red - Isl1 (assay MGI:6144145) and Isl2 (assay MGI:6144251).
Structure Level Pattern Image Note
TS20: spinal cord Strong Punctate 10L , 10O Punctuated pattern of expression typical of mitochondrial expression.
Specimen 10P/S: embryonic day 16.5 (more )
Note: Triple labeled: green - Txn2; purple - Foxp1 (assay MGI:6144147); red - Isl1 (assay MGI:6144145) and Isl2 (assay MGI:6144251).
Structure Level Pattern Image Note
TS24: spinal cord Strong Regionally restricted 10S , 10P Authors report strong ventral expression co-localized in nucleus with motor neuron markers Isl1/2 and Foxp1.
Specimen 10T/W: embryonic day 16.5 (more )
Note: Triple labeled: green - Txn2; purple - Foxp1 (assay MGI:6144147); red - Isl1 (assay MGI:6144145) and Isl2 (assay MGI:6144251).
Structure Level Pattern Image Note
TS24: spinal cord Strong Punctate 10W , 10T Punctuated pattern of expression typical of mitochondrial expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory