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Gene Expression Data
Assay Details
Assay
Reference: J:244896 Stachtea XN, et al., Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis. PLoS One. 2015;10(10):e0140279
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6107845
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: TUJ1
Detection system: Secondary antibody
Results
Specimen C Dse+/+;Dsel-/-: embryonic day 18.5; Dseltm1Mmac/Dseltm1Mmac (more )
Note: Triple labeled: green - Tubb3; red - Dse (assay MGI:6107856); blue - Ptprc (assay MGI:6107858).
Structure Level Pattern Image Note
TS26: nerve Present Regionally restricted 6C Dse+/+;Dsel-/- Expression is in nerve fiber in close proximity to the lymph node.
Specimen C DKO: embryonic day 18.5; Dsetm1Mmac/Dsetm1Mmac, Dseltm1Mmac/Dseltm1Mmac (more )
Note: Triple labeled: green - Tubb3; red - Dse (assay MGI:6107856); blue - Ptprc (assay MGI:6107858).
Structure Level Pattern Image Note
TS26: nerve Present Regionally restricted 6C DKO Expression is the same as in Dse+/+;Dsel-/- lymph nodes.
Specimen D Dse+/+;Dsel-/-: embryonic day 13.5; Dseltm1Mmac/Dseltm1Mmac (more )
Note: Total body 3D light sheet microscopy.
Structure Level Pattern Image Note
TS21: nerve Present 6D bottom middle , 6D top , 6D bottom left , 6D bottom right
Specimen D DKO: embryonic day 13.5; Dsetm1Mmac/Dsetm1Mmac, Dseltm1Mmac/Dseltm1Mmac (more )
Note: Total body 3D light sheet microscopy.
Structure Level Pattern Image Note
TS21: nerve Present 6D DKO bottom right , 6D DKO top , 6D DKO bottom middle , 6D DKO bottom left Expression is the same as in Dse+/+;Dsel-/- lymph nodes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory