Gene Expression Data
Assay Details
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Assay
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Reference:
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J:242973
Ravindran E, et al., Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation. PLoS Genet. 2017 Apr;13(4):e1006746
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5925387
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Gene symbol:
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Barhl1
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Gene name:
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BarH like homeobox 1
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Results
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Specimen
7A:
(close  )
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Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Arhgef2Gt(IST13976A8)Tigm/Arhgef2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Specimen
7B:
(close )
Specimen
7C left:
(close )
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Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Arhgef2Gt(IST13976A8)Tigm/Arhgef2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: red - Barhl1; green - Tlx3 (assay MGI:5925389).
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Specimen
7C right:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cuneate nucleus |
Present |
Regionally restricted |
7C upper right
,
7C lower right
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Expressed in the external cuneate nucleus, which was abnormally enlarged and distributed in the mutant in the rostral medulla.
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Specimen
7D left:
(close )
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Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Arhgef2Gt(IST13976A8)Tigm/Arhgef2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: red - Barhl1; green - Tlx3 (assay MGI:5925389).
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Specimen
7D right:
(close )
Specimen
8A:
(close )
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Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Arhgef2Gt(IST13976A8)Tigm/Arhgef2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Specimen
8B:
(close )
Specimen
8C left:
(close )
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Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Arhgef2Gt(IST13976A8)Tigm/Arhgef2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Specimen
8C right:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cuneate nucleus |
Present |
Regionally restricted |
8C right
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Enlarged expression in external cuneate nucleus, compared with the control.
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Specimen
8D left:
(close )
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Genetic Background:
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involves: C57BL/6N
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Mutant Allele(s):
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Arhgef2Gt(IST13976A8)Tigm/Arhgef2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Specimen
8D right:
(close )
Specimen
S9:
embryonic day 11.0
(more  )
Note: Triple labeled: red - Barhl1; green - Arhgef2 (assay MGI:5925398); cyan - Olig3 (assay MGI:5925390).
Specimen
S9:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Note:
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Triple labeled: red - Barhl1; green - Arhgef2 (assay MGI:5925398); cyan - Olig3 (assay MGI:5925390).
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Analysis Tools