Fn1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:18811 Sheppard AM, et al., Expanding roles for alpha 4 integrin and its ligands in development. Cell Adhes Commun. 1994 Apr;2(1):27-43
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5911109
Gene symbol:	Fn1
Gene name:	fibronectin 1

Antibody:	anti-FN
Detection system:	Secondary antibody coupled to rhodamine

Results

Specimen 2b: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: blood vessel endothelium	Present		2b	Expression is in the aorta.
TS24: arterial system smooth muscle	Present	Regionally restricted	2b	Expression is in the aorta.

Specimen 2c': embryonic day 15.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Image
TS23: blood vessel endothelium	Present	2c'
TS23: lung vascular element	Present	2c'
TS23: smooth muscle tissue	Present	2c'

Specimen 3c': embryonic day 13.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS21: esophagus	Present	Regionally restricted	3c'	Expression is on the muscularis smooth muscle layer that surrounds the submucosa.

Specimen 4a': embryonic day 13.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS21: heart	Present		4a

Specimen 5a': embryonic day 13.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS21: liver	Present		5a'

Specimen 5c': postnatal adult (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS28: spleen white pulp	Present	Regionally restricted	5c'	Expression is in the sheath surrounding the lymph node.

Specimen 5d': postnatal adult (more

)
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).

Structure	Level	Pattern	Image	Note
TS28: spleen	Present		5d'

Specimen 5e': postnatal adult (more

)
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).

Structure	Level	Pattern	Image	Note
TS28: spleen	Present		5e'

Specimen 5f': postnatal adult (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS28: hassall's corpuscle	Present		5f'
TS28: thymus epithelium	Present	Regionally restricted	5f'	Expression is in epithelial reticular cells and their desmosomal processes.

Specimen 6b: postnatal adult (more

)
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).

Structure	Level	Image
TS28: glomerular mesangium	Present	6b
TS28: renal small blood vessel	Present	6b
TS28: renal tubule	Present	6b

Specimen 7a': embryonic day 9.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS15: head mesenchyme	Present	Regionally restricted	7a'	Expression is in the head mesenchyme surrounding the eye.

Specimen 7d': embryonic day 9.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS15: embryo ectoderm	Present	Single cells	7d'	Expression is in migrating melanoblasts.

Specimen 8a': embryonic day 9.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS15: chorionic plate	Present	Regionally restricted	8a'	Expression is on blood vessels in the chorionic plate.
TS15: extraembryonic blood vessel	Present	Regionally restricted	8a'	Expression is on blood vessels in the chorionic plate.
TS15: trophoblast giant cell	Absent		8a'

Specimen 8b': embryonic day 9.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS15: chorionic plate	Present	Regionally restricted	8b'	Expression is on blood vessels in the chorionic plate.
TS15: extraembryonic blood vessel	Present	Regionally restricted	8b'	Expression is on blood vessels in the chorionic plate.
TS15: trophoblast giant cell	Absent		8b'

Specimen 8c': embryonic day 9.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS15: labyrinthine zone	Present		8c'

Specimen 8d': postnatal adult (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS28: blood vessel endothelium	Present	Regionally restricted	8d'	Expression is in vessels in the myometrium.

Specimen 9c': embryonic day 13.5 (more

)
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).

Structure	Level	Pattern	Image	Note
TS21: yolk sac blood vessel	Present		9c'
TS21: yolk sac mesenchyme	Present		9c'

Specimen not shown E13: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: trachea	Present	Regionally restricted		Expression is in the smooth muscle layer.

Specimen not shown: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: aorta endothelium	Present
TS28: aorta smooth muscle	Present
TS28: blood vessel smooth muscle	Present
TS28: small intestine smooth muscle	Present

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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