About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:18811 Sheppard AM, et al., Expanding roles for alpha 4 integrin and its ligands in development. Cell Adhes Commun. 1994 Apr;2(1):27-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5911109
Gene symbol: Fn1
Gene name: fibronectin 1
Antibody: anti-FN
Detection system: Secondary antibody coupled to rhodamine
Results
Specimen 2b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: blood vessel endothelium Present 2b Expression is in the aorta.
TS24: arterial system smooth muscle Present Regionally restricted 2b Expression is in the aorta.

Specimen 2c': embryonic day 15.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS23: blood vessel endothelium Present 2c'
TS23: lung vascular element Present 2c'
TS23: smooth muscle tissue Present 2c'

Specimen 3c': embryonic day 13.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS21: esophagus Present Regionally restricted 3c' Expression is on the muscularis smooth muscle layer that surrounds the submucosa.

Specimen 4a': embryonic day 13.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS21: heart Present 4a

Specimen 5a': embryonic day 13.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS21: liver Present 5a'

Specimen 5c': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS28: spleen white pulp Present Regionally restricted 5c' Expression is in the sheath surrounding the lymph node.

Specimen 5d': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).
Structure Level Pattern Image Note
TS28: spleen Present 5d'

Specimen 5e': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).
Structure Level Pattern Image Note
TS28: spleen Present 5e'

Specimen 5f': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS28: hassall's corpuscle Present 5f'
TS28: thymus epithelium Present Regionally restricted 5f' Expression is in epithelial reticular cells and their desmosomal processes.

Specimen 6b: postnatal adult (more )
Note: Double labeled: red - Fn1; green - Vcam1 (assay MGI:5911016).
Structure Level Pattern Image Note
TS28: glomerular mesangium Present 6b
TS28: renal small blood vessel Present 6b
TS28: renal tubule Present 6b

Specimen 7a': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 7a' Expression is in the head mesenchyme surrounding the eye.

Specimen 7d': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: embryo ectoderm Present Single cells 7d' Expression is in migrating melanoblasts.

Specimen 8a': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: chorionic plate Present Regionally restricted 8a' Expression is on blood vessels in the chorionic plate.
TS15: extraembryonic blood vessel Present Regionally restricted 8a' Expression is on blood vessels in the chorionic plate.
TS15: trophoblast giant cell Absent 8a'

Specimen 8b': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: chorionic plate Present Regionally restricted 8b' Expression is on blood vessels in the chorionic plate.
TS15: extraembryonic blood vessel Present Regionally restricted 8b' Expression is on blood vessels in the chorionic plate.
TS15: trophoblast giant cell Absent 8b'

Specimen 8c': embryonic day 9.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS15: labyrinthine zone Present 8c'

Specimen 8d': postnatal adult (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present Regionally restricted 8d' Expression is in vessels in the myometrium.

Specimen 9c': embryonic day 13.5 (more )
Note: Double labeled: red - Fn1; green - Itga4 (assay MGI:5911014).
Structure Level Pattern Image Note
TS21: yolk sac blood vessel Present 9c'
TS21: yolk sac mesenchyme Present 9c'

Specimen not shown E13: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trachea Present Regionally restricted Expression is in the smooth muscle layer.

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: aorta endothelium Present
TS28: aorta smooth muscle Present
TS28: blood vessel smooth muscle Present
TS28: small intestine smooth muscle Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory