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Gene Expression Data
Assay Details
Assay
Reference: J:206212 Leung KK, et al., Angiotensin II type 2 receptor regulates the development of pancreatic endocrine cells in mouse embryos. Dev Dyn. 2014 Mar;243(3):415-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5904276
Gene symbol: Neurog3
Gene name: neurogenin 3
Antibody: anti-Ngn3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1 e12.5 top: embryonic day 12.5 (more )
Note: Double labeled: green - Neurog3; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS20: pancreas parenchyma Present Single cells 1_top e12.5 Expression is in beta cell progenitors.
Specimen 1 e15.5 top: embryonic day 15.5 (more )
Note: Double labeled: green - Neurog3; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 1_top e15.5 Expression is in beta cell progenitors.
Specimen 1 e17.5 top: embryonic day 17.5 (more )
Note: Double labeled: green - Neurog3; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS25: islets of Langerhans Present Regionally restricted 1_top e17.5 Expression is in beta cell progenitors.
Specimen 1 neonate top: postnatal newborn (more )
Note: Double labeled: green - Neurog3; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS27: islets of Langerhans Absent 1_top neonate
Specimen 1 e12.5 bottom: embryonic day 12.5 (more )
Note: Double labeled: green - Neurog3; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS20: pancreas parenchyma Present Single cells 1_bottom a , 1_bottom a' , 1_bottom e12.5 Expression is in beta cell progenitors.
Specimen 1 e15.5 bottom: embryonic day 15.5 (more )
Note: Double labeled: green - Neurog3; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 1_bottom b' , 1_bottom e15.5 , 1_bottom b Expression is in beta cell progenitors.
Specimen 1 e17.5 bottom: embryonic day 17.5 (more )
Note: Double labeled: green - Neurog3; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS25: islets of Langerhans Present Regionally restricted 1_bottom c , 1_bottom e17.5 , 1_bottom c' Expression is in beta cell progenitors.
Specimen 1 neonate bottom: postnatal newborn (more )
Note: Double labeled: green - Neurog3; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS27: islets of Langerhans Absent 1_bottom neonate
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory