Gene Expression Data
Assay Details
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Assay
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Reference:
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J:240579
Howard SR, et al., IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty. EMBO Mol Med. 2016 Jun;8(6):626-42
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5903411
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Gene symbol:
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Gnrh1
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Gene name:
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gonadotropin releasing hormone 1
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Results
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Specimen
4B/C:
embryonic day 12.5
(more  )
Note: Double labeled: brown - Gnrh1; purple - Igsf10 (assay MGI:5903409).
Specimen
4B/C:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: brown - Gnrh1; purple - Igsf10 (assay MGI:5903409).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: nasal mesenchyme |
Present |
Regionally restricted |
4C
,
4B
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Expressed in neurons exiting the vomeronasal organ and migrating into an Igsf10 strongly positive cell milieu in the nasal mesenchyme.
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| TS20: nerve |
Present |
Regionally restricted |
4C
,
4B
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Expressed in neurons exiting the vomeronasal organ and migrating into an Igsf10 strongly positive cell milieu in the nasal mesenchyme.
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Specimen
4D:
embryonic day 14.5
(more )
Note: Double labeled: brown - Gnrh1; purple - Igsf10 (assay MGI:5903409).
Specimen
4D:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: brown - Gnrh1; purple - Igsf10 (assay MGI:5903409).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: nasal mesenchyme |
Present |
Regionally restricted |
4D
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Expressed in neurons navigating among the Igsf10-positive nasal mesenchyme cells.
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| TS22: nerve |
Present |
Regionally restricted |
4D
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Expressed in neurons navigating among the Igsf10-positive nasal mesenchyme cells.
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Specimen
4J:
embryonic day 17.5
(more )
Note: Double labeled: brown - Gnrh1; purple - Igsf10 (assay MGI:5903409).
Specimen
4J:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: brown - Gnrh1; purple - Igsf10 (assay MGI:5903409).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: nerve |
Present |
Regionally restricted |
4J
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Expressed in neurons located in the medial preoptic area in an Igsf10-negative area.
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| TS25: preoptic area |
Present |
Regionally restricted |
4J
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Expressed in neurons located in the medial preoptic area in an Igsf10-negative area.
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