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Gene Expression Data
Assay Details
Assay
Reference: J:159506 Sun P, et al., Cytokeratin expression during mouse embryonic and early postnatal mammary gland development. Histochem Cell Biol. 2010 Feb;133(2):213-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5827739
Gene symbol: Krt6
Gene name: keratin 6
Antibody: anti-K6
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 1C: embryonic day 16.5 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:5827742).
Structure Level Pattern Image Note
TS24: mammary gland primordium Strong Regionally restricted 1C Strong expression in nipple sheath. Scattered positive cells also in nipple skin between the sheath.
TS24: mammary sprout Strong Regionally restricted 1C Expression in upper portion of the mammary sprout.
Specimen 1F: embryonic day 18.5 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:5827742).
Structure Level Pattern Image Note
TS26: mammary gland Present Regionally restricted 1F Expressed in a luminal-like location.
Specimen 1G: embryonic day 18.5 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:5827742).
Structure Level Pattern Image Note
TS26: mammary gland Present 1G Expressed in a luminal-like location.
Specimen 2A/B: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: mammary gland Present Regionally restricted 2A/B Mostly in the inner core of the ductal termini.
Specimen 2C: postnatal day 14 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:5827742).
Structure Level Pattern Image Note
TS28: mammary gland duct Present Regionally restricted 2C Mostly in the inner core of the ductal termini, and some co-stained for Krt14.
Specimen 2D: postnatal day 18 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:5827742).
Structure Level Pattern Image Note
TS28: mammary gland Present Regionally restricted 2D Expressed in inner cells of the ductal termini, and a few cells were double positive for Krt6 and Krt14.
Specimen 2E: postnatal week 3 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:5827742).
Structure Level Pattern Image Note
TS28: mammary gland duct Present Regionally restricted 2E Expressed in terminal end buds, and in scattered ductal epithelial cells. Only a few cells co-stained for Krt14.
Specimen 2F: postnatal week 12 (more )
Note: Double labeled: green - Krt6; red - Krt14 (assay MGI:5827742).
Structure Level Pattern Image Note
TS28: mammary gland Absent 2F Mature mammary gland.
Specimen not shown: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: mammary gland Present Regionally restricted Mostly in the inner core of the ductal termini, and some co-stained for Krt14.
Specimen not shown: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: mammary gland duct Present Expressed in terminal end buds and ductal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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