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Gene Expression Data
Assay Details
Assay
Reference: J:124347 Heinzel K, et al., The Foxn1-dependent transcripts PCOLCE2 and mPPP1R16B are not required for normal thymopoiesis. Eur J Immunol. 2007 Sep;37(9):2562-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5824276
Gene symbol: Krt8
Gene name: keratin 8
Antibody: TROMA 1
Results
Specimen 2H WT: postnatal week 4-6 (more )
Note: Double labeled: red - Krt8; green - Krt5 (assay MGI:5824277).
Structure Level Pattern Image Note
TS28: thymus cortex Present 2H WT Expression in cortical components.
Specimen 2H POLCE2 KO: postnatal week 4-6; Pcolce2tm1Ccb/Pcolce2tm1Ccb (more )
Note: Double labeled: red - Krt8; green - Krt5 (assay MGI:5824277).
Structure Level Pattern Image Note
TS28: thymus cortex Present 2H PCOLCE2 KO Authors report normal distribution of expression in mutant mice.
Specimen 3K PPP1R16B KO: postnatal week 4-6; Ppp1r16btm1Ccb/Ppp1r16btm1Ccb (more )
Note: Triple labeled: red - Krt8; green - Krt5 (assay MGI:5824277); blue - UEA-1.
Structure Level Pattern Image Note
TS28: thymus cortex Present 3K PPP1R16B KO Authors report no evidence for abnormal thymus or T cell development.
Specimen 4B dKO: postnatal week 4-6; Pcolce2tm1Ccb/Pcolce2tm1Ccb, Ppp1r16btm1Ccb/Ppp1r16btm1Ccb (more )
Note: Triple labeled: red - Krt8; green - Krt5 (assay MGI:5824277); blue - UEA-1.
Structure Level Pattern Image Note
TS28: thymus cortex Present 4B dKO K8 , 4B dKO merge (upper) Authors report stromal and lymphoid cells located in correct thymic niches.
Specimen 4B WT: postnatal week 4-6 (more )
Note: Triple labeled: red - Krt8; green - Krt5 (assay MGI:5824277); blue - UEA-1.
Structure Level Pattern Image Note
TS28: thymus cortex Present 4B WT merge (upper) , 4B WT K8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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