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Gene Expression Data
Assay Details
Assay
Reference: J:118119 Sakaki-Yumoto M, et al., The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. Development. 2006 Aug;133(15):3005-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5792922
Gene symbol: Pou5f1
Gene name: POU domain, class 5, transcription factor 1
Antibody: anti-Oct3/4 (C-10; sc-5279)
Assay notes: Two antibodies were described MGI:3702926 and MGI:5792906. Either antibody could have been used in this assay.
Results
Specimen 2A +/-: embryonic day 3.5; Sall4tm1Ryn/Sall4+ (more )
Note: Blastocyst. Double labeled: red - Pou5f1; green - Cdx2 (assay MGI:5792923).
Structure Level Pattern Image Note
TS4: inner cell mass Present 2A +/-
Specimen 2A -/-: embryonic day 3.5; Sall4tm1Ryn/Sall4tm1Ryn (more )
Note: Blastocyst. Double labeled: red - Pou5f1; green - Cdx2 (assay MGI:5792923).
Structure Level Pattern Image Note
TS4: inner cell mass Present 2A -/- Expression in the homozygote was not altered from wild type or heterozygotes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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