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Gene Expression Data
Assay Details
Assay
Reference: J:225272 Zhou J, et al., Accelerated reproductive aging in females lacking a novel centromere protein SYCP2L. Hum Mol Genet. 2015 Nov;24(22):6505-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5785023
Gene symbol: Sycp2l
Gene name: synaptonemal complex protein 2-like
Antibody: UP2395
Results
Specimen 1B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: primary oocyte Present 1B Immunostaining was noted in the majority of oocytes and absent from a subset. Expression was nuclear.
Specimen 1C: postnatal day 0; Sycp2ltm1Jw/Sycp2ltm1Jw (more )
Structure Level Pattern Image Note
TS27: primary oocyte Absent 1C
Specimen 1D: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: oocyte of primordial follicle Present 1D Expression was nuclear.
Specimen 1E: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: oocyte of primary follicle Present 1E Expression was nuclear.
Specimen 1F: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: oocyte of secondary follicle Present 1F Expression was nuclear.
Specimen 1G: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: oocyte of tertiary follicle Present 1G Expression was nuclear.
Specimen 2A: postnatal newborn (more )
Note: Double labeled: green - Sycp2l; red - Sycp2 (assay MGI:5787636). Nuclear spread in pachytene stage oocyte.
Structure Level Pattern Image Note
TS27: primary oocyte Absent 2A Sycp2l , 2A Merge Signal was absent in pachytene stage oocyte.
Specimen 2B: postnatal newborn (more )
Note: Double labeled: green - Sycp2l; red - Sycp2 (assay MGI:5787636). Nuclear spread in early diplotene stage oocyte.
Structure Level Pattern Image Note
TS27: primary oocyte Absent 2B Sycp2l , 2B Merge Signal was absent in early diplotene stage oocyte.
Specimen 2C: postnatal newborn (more )
Note: Double labeled: green - Sycp2l; red - Sycp2 (assay MGI:5787636). Nuclear spread in late diplotene stage oocyte.
Structure Level Pattern Image Note
TS27: primary oocyte Present 2C Merge , 2C Sycp2l Expression was detected in the synaptonemal complex lateral elements in late diplotene stage oocyte. Signal existed as a pair of bright dots at one end of the lateral elements.
Specimen 2D: postnatal newborn (more )
Note: Double labeled: green - Sycp2l; red - Ss18l1 (assay MGI:5787653). Nuclear spread in late diplotene stage oocyte.
Structure Level Pattern Image Note
TS27: primary oocyte Present 2D Merge , 2D Sycp2l Expression was localized in the centromere.
Specimen 2E: postnatal adult (more )
Note: Double labeled: green - Sycp2l; red - Ss18l1 (assay MGI:5787653). Nuclear spread in germinal vesicle stage oocyte.
Structure Level Pattern Image Note
TS28: primary oocyte Present 2E Sycp2l , 2E Merge Expression was localized in the centromere.
Specimen S1C +/+: postnatal day 10 (more )
Note: Double labeled: green - Sycp2l; red - Stk31 (assay MGI:5787654).
Structure Level Pattern Image Note
TS28: ovary Present S1C Sycp2l+/+ Sycp2l , S1C Sycp2l+/+ Merge
Specimen S1C -/-: postnatal day 10; Sycp2ltm1Jw/Sycp2ltm1Jw (more )
Note: Double labeled: green - Sycp2l; red - Stk31 (assay MGI:5787654).
Structure Level Pattern Image Note
TS28: ovary Absent S1C Sycp2l-/- Sycp2l , S1C Sycp3l-/- Merge
Specimen S2 Leptotene: embryonic day 15.5 (more )
Note: Double labeled: green - Sycp2l; red - Sycp2 (assay MGI:5787636). Nuclear spread in leptotene stage oocyte.
Structure Level Pattern Image Note
TS23: meiotic germ cell of ovary Absent S2_Leptotene Merge , S2_Leptotene Sycp2l
Specimen S2 Zygotene: embryonic day 15.5 (more )
Note: Double labeled: green - Sycp2l; red - Sycp2 (assay MGI:5787636). Nuclear spread in zygotene stage oocyte.
Structure Level Pattern Image Note
TS23: meiotic germ cell of ovary Absent S2_Zygotene Merge , S2_Zygotene Sycp2l
Specimen S2 Late diplotene: embryonic day 18.5 (more )
Note: Double labeled: green - Sycp2l; red - Sycp2 (assay MGI:5787636). Nuclear spread in late diplotene stage oocyte.
Structure Level Pattern Image Note
TS26: oocyte Present S2_Late diplotene Sycp2l , S2_Late diplotene Merge Expression was localized to the synaptonemal complex in late diplotene oocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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