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Gene Expression Data
Assay Details
Assay
Reference: J:174119 Glickstein SB, et al., Differences in cyclin D2 and D1 protein expression distinguish forebrain progenitor subsets. Cereb Cortex. 2007 Mar;17(3):632-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5751978
Gene symbol: Ccnd2
Gene name: cyclin D2
Antibody: Anti-Cyclin D2 (Ab-4 MS-221)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3H/I: embryonic day 14.5 (more )
Note: Double labeled: red - Ccnd2; green - Ccnd1 (assay MGI:5751977).
Structure Level Pattern Image Note
TS22: lateral ganglionic eminence ventricular zone Present Regionally restricted 3I , 3H In the ventricular zone, most progenitors expressed either Ccnd1 or Ccnd2, but a few cells expressed both cyclins.
TS22: medial ganglionic eminence ventricular zone Present Regionally restricted 3I , 3H In the ventricular zone, most progenitors expressed either Ccnd1 or Ccnd2, but a few cells expressed both cyclins.
TS22: medial ganglionic eminence subventricular zone Present 3I , 3H In the medial ganglionic eminence, immunopositive cells are predominantly in the subventricular zone.
Specimen 3K/L: embryonic day 14.5; Ccnd2tm1Wbg/Ccnd2tm1Wbg (more )
Note: Double labeled: red - Ccnd2; green - Ccnd1 (assay MGI:5751977).
Structure Level Pattern Image Note
TS22: lateral ganglionic eminence ventricular zone Present Regionally restricted 3L , 3K In the ventricular zone, most progenitors expressed either Ccnd1 or Ccnd2, but a few cells expressed both cyclins.
TS22: medial ganglionic eminence ventricular zone Present Regionally restricted 3L , 3K In the ventricular zone, most progenitors expressed either Ccnd1 or Ccnd2, but a few cells expressed both cyclins.
TS22: medial ganglionic eminence subventricular zone Present Regionally restricted 3K , 3L In the medial ganglionic eminence, immunopositive cells are predominantly in the subventricular zone.
Specimen S1B/C: embryonic day 14.5 (more )
Note: Double labeled: red - Ccnd2; green - Tbr1 (assay MGI:5752047).
Structure Level Pattern Image Note
TS22: cerebral cortex Present S1C , S1B Generally, expression was distinct from Tbr1 expression. Rare cells were seen that were labeled with both antibodies.
Specimen S1E/F: embryonic day 14.5 (more )
Note: Double labeled: red - Ccnd2; green - Tbr1 (assay MGI:5752047).
Structure Level Pattern Image Note
TS22: cerebral cortex Present S1E , S1F Generally, expression was distinct from Tbr1 expression. Rare cells were seen that were labeled with both antibodies.
Specimen S4A/C: embryonic day 12.5 (more )
Note: Double labeled: red - Ccnd2; green - Ccnd1 (assay MGI:5751977).
Structure Level Pattern Image Note
TS20: medial ganglionic eminence ventricular zone Present Regionally restricted S4C , S4A Most progenitors expressed either Ccnd1 or Ccnd2, but a few cells expressed both cyclins.
Specimen S4J/L: embryonic day 12.5 (more )
Note: Double labeled: red - Ccnd2; green - Olig2 (assay MGI:5752065).
Structure Level Pattern Image Note
TS20: medial ganglionic eminence ventricular zone Present S4J , S4L Expression colocalized with cells expressing Olig2.
TS20: medial ganglionic eminence subventricular zone Present Regionally restricted S4J , S4L In the subventricular zone, cells expressed either Olig2 or Ccnd2.
Specimen S4N/O: embryonic day 14.5 (more )
Note: Double labeled: red - Ccnd2; green - Olig2 (assay MGI:5752065).
Structure Level Pattern Image Note
TS22: medial ganglionic eminence ventricular zone Present S4N , S4O Expression colocalized with cells expressing Olig2.
TS22: medial ganglionic eminence subventricular zone Present Regionally restricted S4O , S4N Cells expressed either Olig2 or Ccnd2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
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