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Gene Expression Data
Assay Details
Assay
Reference: J:215516 Dominguez MH, et al., POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex. Cereb Cortex. 2013 Nov;23(11):2632-43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5751512
Gene symbol: Satb2
Gene name: special AT-rich sequence binding protein 2
Antibody: anti-Satb2
Detection system: Secondary antibody
Results
Specimen S2A: embryonic day 15.5 (more )
Note: Triple labeled: red - Satb2; blue - Bcl11b (assay MGI:5751509); green - Cux1 (assay MGI:5751513).
Structure Level Pattern Image Note
TS23: cortical plate Present Regionally restricted S2A Expression in cells migrating into layers II/III of cortical plate.
Specimen S2A': embryonic day 15.5 (more )
Note: Double labeled: red - Satb2; green - Cux1 (assay MGI:5751513).
Structure Level Pattern Image Note
TS23: cortical plate Present Regionally restricted S2A' Expression in cells migrating into layers II/III of cortical plate.
Specimen S2B'': embryonic day 15.5 (more )
Note: Double labeled: red - Satb2; green - Pou3f3 (assay MGI:5751507) and Pou3f2 (assay MGI:5751523).
Structure Level Pattern Image Note
TS23: cortical plate Present Regionally restricted S2B'' Expression in cells migrating into layers II/III of cortical plate, and cells that might represent a population of layer V corticospinal motor neurons.
Specimen S2B''': embryonic day 15.5 (more )
Note: Double labeled: red - Satb2; green - Ctip2 (Bcl11b assay MGI:5751551).
Structure Level Pattern Image Note
TS23: cortical plate Present Regionally restricted S2B''' Expression in cells migrating into layers II/III of cortical plate, and cells that might represent a population of layer V corticospinal motor neurons.
Specimen S2C: postnatal day 0 (more )
Note: Triple labeled: red - Satb2; green - Cux1 (assay MGI:5751513); blue - Pou3f2 (assay MGI:5751517) and Pou3f3 (assay MGI:5751508).
Structure Level Pattern Image Note
TS27: cortical layer II Present S2C Expression in layer II/III and presumptive layer IV cells.
TS27: cortical layer III Present S2C Expression in layer II/III and presumptive layer IV cells.
TS27: cortical layer IV Present S2C Expression in layer II/III and presumptive layer IV cells.
Specimen S2C': postnatal day 0 (more )
Note: Double labeled: red - Satb2; green - Cux1 (assay MGI:5751513).
Structure Level Pattern Image Note
TS27: cortical layer II Present S2C' Expression in layer II/III and presumptive layer IV cells.
TS27: cortical layer III Present S2C' Expression in layer II/III and presumptive layer IV cells.
TS27: cortical layer IV Present S2C' Expression in layer II/III and presumptive layer IV cells.
Specimen S2D'': postnatal day 0 (more )
Note: Double labeled: red - Satb2; green - Pou3f3 (assay MGI:5751507) and Pou3f2 (assay MGI:5751523).
Structure Level Pattern Image Note
TS27: cortical layer V Present Regionally restricted S2D'' Expression in upper portions of layer V.
Specimen S2D''': postnatal day 0 (more )
Note: Double labeled: red - Satb2; green - Ctip2 (Bcl11b assay MGI:5751551).
Structure Level Pattern Image Note
TS27: cortical layer V Present Regionally restricted S2D''' Expression in upper portions of layer V.
Specimen S3A: embryonic day 14.5 (more )
Note: Double labeled: red - Satb2; green - Pou3f3 (assay MGI:5751507) and Pou3f2 (assay MGI:5751523).
Structure Level Pattern Image Note
TS22: neocortex Present Regionally restricted S3A Merge , S3A Satb2 Expression in migrating upper layer cells.
Specimen S3E: postnatal day 0 (more )
Note: Double labeled: red - Satb2; green - Pou3f3 (assay MGI:5751507) and Pou3f2 (assay MGI:5751523).
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted S3E Satb2 , S3E Merge Expression in upper layer cells.
Specimen S3J: postnatal day 0 (more )
Note: Double labeled: red - Satb2; green - Tbr1 (assay MGI:5751514).
Structure Level Pattern Image Note
TS27: neocortex Present Widespread S3J Satb2 , S3J Merge Expression in numerous cells in all layers.
TS27: cortical layer VI Present Regionally restricted S3J Satb2 , S3J Merge Expression in subset of layer VI cells.
Specimen S3K: embryonic day 14.5 (more )
Note: Triple labeled: red - Satb2; blue - Bcl11b (assay MGI:5751509); green - Tbr1 (assay MGI:5751514).
Structure Level Pattern Image Note
TS22: cortical plate Present Regionally restricted S3K Expression in nuclei of cells migrating radially toward superficial strata of widening cortical plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory