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Gene Expression Data
Assay Details
Assay
Reference: J:191238 Su YQ, et al., Meiosis arrest female 1 (MARF1) has nuage-like function in mammalian oocytes. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18653-60
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5749218
Gene symbol: H2ax
Gene name: H2A.X variant histone
Results
Specimen 4A: postnatal (more )
Note: Double labeled with anti-centromere antibody (green).
Structure Level Pattern Image Note
TS28: primary oocyte Present 4A

Specimen 4B: postnatal; Marf1m1Rpg/Marf1m1Rpg (more )
Note: Double labeled with anti-centromere antibody (green).
Structure Level Pattern Image Note
TS28: primary oocyte Present 4B The number of positive foci has increased in this mutant oocyte.

Specimen S2 WT gH2AX Leptonema: postnatal day 0 (more )
Note: Triple labeled: red - H2ax; purple - Sycp3 (assay MGI:5749224); green - anti-centromere antibody.
Structure Level Pattern Image Note
TS27: primary oocyte Present S2_WT gH2AX Leptonema , S2_WT Merge Leptonema

Specimen S2 WT gH2AX Zygonema: postnatal day 0 (more )
Note: Triple labeled: red - H2ax; purple - Sycp3 (assay MGI:5749224); green - anti-centromere antibody.
Structure Level Pattern Image Note
TS27: primary oocyte Present S2_WT gH2AX Zygonema , S2_WT Merge Zygonema

Specimen S2 WT gH2AX Pachynema: postnatal day 0 (more )
Note: Triple labeled: red - H2ax; purple - Sycp3 (assay MGI:5749224); green - anti-centromere antibody.
Structure Level Pattern Image Note
TS27: primary oocyte Present S2_WT Merge Pachynema , S2_WT gH2AX Pachynema

Specimen S2 Mutant gH2AX Leptonema: postnatal day 0; Marf1m1Rpg/Marf1m1Rpg (more )
Note: Triple labeled: red - H2ax; purple - Sycp3 (assay MGI:5749224); green - anti-centromere antibody.
Structure Level Pattern Image Note
TS27: primary oocyte Present S2_Mutant Merge Leptonema , S2_Mutant gH2AX Leptonema Expression in this mutant is the same as in wild-type embryos.

Specimen S2 Mutant gH2AX Zygonema: postnatal day 0; Marf1m1Rpg/Marf1m1Rpg (more )
Note: Triple labeled: red - H2ax; purple - Sycp3 (assay MGI:5749224); green - anti-centromere antibody.
Structure Level Pattern Image Note
TS27: primary oocyte Present S2_Mutant Merge Zygonema , S2_Mutant gH2AX Zygonema Expression in this mutant is the same as in wild-type embryos.

Specimen S2 Mutant gH2AX Pachynema: postnatal day 0; Marf1m1Rpg/Marf1m1Rpg (more )
Note: Triple labeled: red - H2ax; purple - Sycp3 (assay MGI:5749224); green - anti-centromere antibody.
Structure Level Pattern Image Note
TS27: primary oocyte Present S2_Mutant Merge Pachynema , S2_Mutant gH2AX Pachynema Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory