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Gene Expression Data
Assay Details
Assay
Reference: J:211312 Woo SH, et al., Piezo2 is required for Merkel-cell mechanotransduction. Nature. 2014 May 29;509(7502):622-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5697832
Gene symbol: S100b
Gene name: S100 protein, beta polypeptide, neural
Antibody: anti-S-100 (Z0311)
Detection system: Secondary antibody
Results
Specimen Ext. 4H: postnatal; Piezo2tm2.2Apat/Piezo2tm2.2Apat (more )
Note: Dorsal skin. Double labeled: red - S100b; green - Nefh (assay MGI:5697548).
Structure Level Pattern Image Note
TS28: peripheral nervous system Present Single cells Extended Data 4H S100 , Extended Data 4H Merge Expression is present in Schwann cells in Merkel cell-neurite complexes in touch domes in hairy skin.
Specimen Ext. 4I: postnatal; Piezo2tm2.2Apat/Piezo2tm2.2Apat (more )
Note: Foot pad. Double labeled: red - S100b; green - Nefh (assay MGI:5697548).
Structure Level Pattern Image Note
TS28: peripheral nervous system Present Single cells Extended Data 4I S100 , Extended Data 4I Merge Expression is present in Schwann cells in Merkel cell-neurite complexes in glabrous (nonhairy) skin.
Specimen Ext. 4M: postnatal; Piezo2tm2.2Apat/Piezo2tm2.2Apat, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant. Dorsal skin. Double labeled: red - S100b; green - Nefh (assay MGI:5697548).
Structure Level Pattern Image Note
TS28: peripheral nervous system Present Single cells Extended Data 4M Merge , Extended Data 4M S100 As in wild type, expression is present in Schwann cells in Merkel cell-neurite complexes in touch domes in hairy skin.
Specimen Ext. 4N: postnatal; Piezo2tm2.2Apat/Piezo2tm2.2Apat, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant. Dorsal skin. Double labeled: red - S100b; green - Nefh (assay MGI:5697548).
Structure Level Pattern Image Note
TS28: peripheral nervous system Present Single cells Extended Data 4N S100 , Extended Data 4N Merge As in wild type, expression is present in Schwann cells in Merkel cell-neurite complexes in touch domes in hairy skin.
Specimen Ext. 4O: postnatal; Piezo2tm2.2Apat/Piezo2tm2.2Apat, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant. Foot pad. Double labeled: red - S100b; green - Nefh (assay MGI:5697548).
Structure Level Pattern Image Note
TS28: peripheral nervous system Present Single cells Extended Data 4O S100 , Extended Data 4O Merge As in wild type, expression is present in Schwann cells in Merkel cell-neurite complexes in glabrous (nonhairy) skin.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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