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Gene Expression Data
Assay Details
Assay
Reference: J:182578 Kay JN, et al., MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Nature. 2012 Mar 22;483(7390):465-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5660812
Gene symbol: Calb1
Gene name: calbindin 1
Results
Specimen 1c right: postnatal day 5 (more )
Note: Double labeled: green - Calb1; red - Megf10 (assay MGI:5660813).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 1c right Expression was detected in starburst amacrine cells and horizontal cells.
TS28: retina ganglion cell layer Present Regionally restricted 1c right Expression was detected in starburst amacrine cells.
Specimen 3b right: postnatal day 5 (more )
Note: Double labeled: green - Calb1; red - Megf11 (assay MGI:5660881).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3b right Expression was detected in starburst amacrine cells and horizontal cells.
TS28: retina ganglion cell layer Present Regionally restricted 3b right Expression was detected in starburst amacrine cells.
Specimen 3c right: postnatal day 7 (more )
Note: Double labeled: green - Calb1; red - Megf11 (assay MGI:5660881).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3c right Expression was detected in starburst amacrine cells and horizontal cells.
TS28: retina ganglion cell layer Present Regionally restricted 3c right Expression was detected in starburst amacrine cells.
Specimen 3d right: postnatal day 14 (more )
Note: Double labeled: green - Calb1; red - Megf11 (assay MGI:5660881).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3d right Expression was detected in starburst amacrine cells and horizontal cells.
TS28: retina ganglion cell layer Present Regionally restricted 3d right Expression was detected in starburst amacrine cells.
Specimen 3e: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3e Expression was detected in horizontal cells, which were distributed evenly.
Specimen 3f: postnatal day 15; Megf10tm1a(KOMP)Jrs/Megf10tm1a(KOMP)Jrs (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3f Expression was detected in horizontal cells, which had subtle changes in the regular spacing in the mutant.
Specimen 3g: postnatal day 15; Megf11tm1a(EUCOMM)Wtsi/Megf11tm1a(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3g Expression was detected in horizontal cells, which had subtle changes in the regular spacing in the mutant.
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 3h Expression was detected in horizontal cells, which showed marked disorganization in the double mutant.
Specimen S1b right: postnatal day 7 (more )
Note: Double labeled: green - Calb1; red - Megf10 (assay MGI:5660813).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S1b right Expression was detected in starburst amacrine cells and horizontal cells.
TS28: retina ganglion cell layer Present Regionally restricted S1b right Expression was detected in starburst amacrine cells.
Specimen S5a wild type: postnatal day 0 (more )
Note: Also stained for Slc18a3 (assay MGI:5660922).
Structure Level Pattern Image Note
TS27: retina layer Present Regionally restricted S5a left Expression was detected in starburst amacrine cells.
Specimen S5a -/-: postnatal day 0; Megf10tm1a(KOMP)Jrs/Megf10tm1a(KOMP)Jrs (more )
Note: Also stained for Slc18a3 (assay MGI:5660922).
Structure Level Pattern Image Note
TS27: retina layer Present Regionally restricted S5a right Expression was detected in starburst amacrine cells. Soma disorganization was evident at P0 in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory