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Gene Expression Data
Assay Details
Assay
Reference: J:124197 Kiyozumi D, et al., Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1. Matrix Biol. 2007 Jul;26(6):456-462
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5578519
Gene symbol: Lamc1
Gene name: laminin, gamma 1
Antibody: mAb 1914
Detection system: Secondary antibody coupled to rhodamine
Assay notes: Cryosections were fixed in absolute ethanol.
Results
Specimen 2B Frem3: postnatal week 9 (more )
Note: Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 2B Frem3 Expression is at the basement membrane.

Specimen 2B Fras1: postnatal week 9 (more )
Note: Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 2B Fras1 Expression is at the basement membrane.

Specimen 2B Frem2: postnatal week 9 (more )
Note: Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 2B Frem2 Expression is at the basement membrane.

Specimen 2B QBRICK/Frem1: postnatal week 9 (more )
Note: Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 2B QBRICK/Frem1 Expression is at the basement membrane.

Specimen 2C Fem3: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C Frem3 Expression is at the basement membrane.

Specimen 2C Fras1: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C Fras1 Expression is at the basement membrane.

Specimen 2C Frem2: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C Frem2 Expression is at the basement membrane.

Specimen 2C QBERICK/Frem1: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C QBRICK/Frem1 Expression is at the basement membrane.

Specimen 2D Frem3: postnatal adult; Frem2my/Frem2my (more )
Note: Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 2D Frem3 Expression is at the basement membrane.

Specimen 2D Fras1: postnatal adult (more )
Note: Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 2D Fras1 Expression is at the basement membrane.

Specimen 2D Frem2: postnatal adult (more )
Note: Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 2D Frem2 Expression is at the basement membrane.

Specimen 2D QBRICK/Frem1: postnatal adult (more )
Note: Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 2D QBRICK/Frem1 Expression is at the basement membrane.

Specimen 2E Frem3: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 2E Frem3 Expression is at the basement membrane.

Specimen 2E Fras1: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 2E Fras1 Expression is at the basement membrane.

Specimen 2E Frem2: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 2E Frem2 Expression is at the basement membrane.

Specimen 2E QBRICK/Frem1: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 2E QBRICK/Frem1 Expression is at the basement membrane.

Specimen 3A first: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 3A bottom first Expression is at the basement membrane.
TS25: hair follicle Present Regionally restricted 3A bottom first Expression is at the basement membrane.

Specimen 3A second: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 3A bottom second Expression is at the basement membrane.
TS25: hair follicle Present Regionally restricted 3A bottom second Expression is at the basement membrane.

Specimen 3A third: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 3A bottom third Expression is at the basement membrane.
TS25: hair follicle Present Regionally restricted 3A bottom third Expression is at the basement membrane.

Specimen 3A fourth: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 3A bottom fourth Expression is at the basement membrane.
TS25: hair follicle Present Regionally restricted 3A bottom fourth Expression is at the basement membrane.

Specimen 3B Frem3: postnatal week 4 (more )
Note: Panels at the right are higher magnifications of the boxed areas. Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 3B Frem3 Expression is at the basement membrane.
TS28: epidermis Present Regionally restricted 3B Frem3 Expression is at the basement membrane.
TS28: hair outer root sheath Present Regionally restricted 3B Frem3 Expression is at the basement membrane.

Specimen 3B Fras1: postnatal week 4 (more )
Note: Panels at the right are higher magnifications of the boxed areas. Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 3B Fras1 Expression is at the basement membrane.
TS28: epidermis Present Regionally restricted 3B Fras1 Expression is at the basement membrane.
TS28: hair outer root sheath Present Regionally restricted 3B Fras1 Expression is at the basement membrane.

Specimen 3B Frem2: postnatal week 4 (more )
Note: Panels at the right are higher magnifications of the boxed areas. Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 3B Frem2 Expression is at the basement membrane.
TS28: epidermis Present Regionally restricted 3B Frem2 Expression is at the basement membrane.
TS28: hair outer root sheath Present Regionally restricted 3B Frem2 Expression is at the basement membrane.

Specimen 3B QBRICK/Frem1: postnatal week 4 (more )
Note: Panels at the right are higher magnifications of the boxed areas. Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 3B QBRICK/Frem1 Expression is at the basement membrane.
TS28: epidermis Present Regionally restricted 3B QBRICK/Frem1 Expression is at the basement membrane.
TS28: hair outer root sheath Present Regionally restricted 3B QBRICK/Frem1 Expression is at the basement membrane.

Specimen 4A Qbrick/Frem1+/- first: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1+/- LNg1 first Expression is at the basement membrane.

Specimen 4A Qbrick/Frem1+/- second: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1+/- LNg1 second Expression is at the basement membrane.

Specimen 4A Qbrick/Frem1+/- third: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1+/- LNg1 third Expression is at the basement membrane.

Specimen 4A Qbrick/Frem1+/- fourth: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1+/- LNg1 fourth Expression is at the basement membrane.

Specimen 4A Qbrick/Frem1-/- first: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1-/- LNg1 first Expression is at the basement membrane.

Specimen 4A Qbrick/Frem1-/- second: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1-/- LNg1 second Expression is at the basement membrane.

Specimen 4A Qbrick/Frem1-/- third: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1-/- LNg1 third Expression is at the basement membrane.

Specimen 4A Qbrick/Frem1-/- fourth: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1-/- LNg1 fourth Expression is at the basement membrane.

Specimen 4A Frem2my/+ first: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/+ LNg1 first Expression is at the basement membrane.

Specimen 4A Frem2my/+ second: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/+ LNg1 second Expression is at the basement membrane.

Specimen 4A Frem2my/+ third: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/+ LNg1 third Expression is at the basement membrane.

Specimen 4A Frem2my/+ fourth: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/+ LNg1 fourth Expression is at the basement membrane.

Specimen 4A Frem2my/my first: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/my LNg1 first Expression is at the basement membrane.

Specimen 4A Frem2my/my second: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/my LNg1 second Expression is at the basement membrane.

Specimen 4A Frem2my/my third: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/my LNg1 third Expression is at the basement membrane.

Specimen 4A Frem2my/my fourth: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/my LNg1 fourth Expression is at the basement membrane.

Specimen 4A Grip1eb/+ first: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/+ LNg1 first Expression is at the basement membrane.

Specimen 4A Grip1eb/+ second: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/+ LNg1 second Expression is at the basement membrane.

Specimen 4A Grip1eb/+ third: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/+ LNg1 third Expression is at the basement membrane.

Specimen 4A Grip1eb/+ fourth: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/+ LNg1 fourth Expression is at the basement membrane.

Specimen 4A Grip1eb/eb first: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/eb LNg1 first Expression is at the basement membrane.

Specimen 4A Grip1eb/eb second: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/eb LNg1 second Expression is at the basement membrane.

Specimen 4A Grip1eb/eb third: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/eb LNg1 third Expression is at the basement membrane.

Specimen 4A Grip1eb/eb fourth: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/eb LNg1 fourth Expression is at the basement membrane.

Specimen 4B Frem2my/+: embryonic day 13.5; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS21: epidermis Present Regionally restricted 4B Frem2my/+ LNg1 Expression is at the basement membrane.

Specimen 4B Frem2my/my: embryonic day 13.5; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS21: epidermis Present Regionally restricted 4B Frem2my/my LNg1 Expression is at the basement membrane.

Specimen 4C Grip1eb/+: embryonic day 14.5; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS22: epidermis Present Regionally restricted 4C Grip1eb/+ LNg1 Expression is at the basement membrane.

Specimen 4C Grip1eb/eb: embryonic day 14.5; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS22: epidermis Present Regionally restricted 4C Grip1eb/eb LNg1 Expression is at the basement membrane.


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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory