anti-phospho-ERK1/2 (D13.14.4E; #4370) MGI Antibody Detail

Antibody
Detail

Antibody

Name:	anti-phospho-ERK1/2 (D13.14.4E; #4370)
Host:	rabbit
Type:	Monoclonal
Class:	IgG
Note:	This antibody was obtained from Cell Signaling Technology (#4370). Detects endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when dually phosphorylated at Thr202 and Tyr204 of Erk1 (Thr185 and Tyr187 of Erk2), and singly phosphorylated at Thr202. This antibody does not cross-react with the corresponding phosphorylated residues of either JNK/SAPK or p38 MAP kinases.
MGI Accession ID:	MGI:5574505

Antigen

Name:	p44 MAP kinase
Species:	human
Region covered:	residues surrounding Thr202/Tyr204
Note:	synthetic phosphopeptide

Genes

Mapk1 mitogen-activated protein kinase 1
Mapk3 mitogen-activated protein kinase 3

Expression

Gene Expression Data (146 results)

References

J:160674 Mai S, et al., Dev Dyn. 2010 Jun;239(6):1888-900
J:174095 Cai Z, et al., Mol Cell Biol. 2011 Jul;31(14):2973-83
J:310134 Adachi K, et al., Mol Cell. 2013 Nov 7;52(3):380-92
J:218234 Wurm S, et al., Genes Dev. 2015 Jan 15;29(2):144-56
J:232444 Li S, et al., Biol Reprod. 2016 Feb;94(2):41
J:267540 Cesario JM, et al., Dev Biol. 2018 Nov 15;443(2):103-116
J:320347 Jiang K, et al., Sci Rep. 2018 Sep 25;8(1):14344
J:297585 Yang Y, et al., Nucleic Acids Res. 2020 Nov 18;48(20):11452-11467
J:308695 Talley MJ, et al., Front Cell Dev Biol. 2021;9:673995
J:363525 Conrad L, et al., Development. 2021 May 1;148(9)
J:333283 Guan N, et al., Kidney Int. 2022 Jul;102(1):108-120
J:353621 Patel VN, et al., Nat Commun. 2024 Aug 31;15(1):7584

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24