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Gene Expression Data
Assay Details
Assay
Reference: J:90277 Yao HH, et al., Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn. 2004 Jun;230(2):210-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5528682
Gene symbol: Sycp1
Gene name: synaptonemal complex protein 1
Antibody: Anti-Syn/Cor
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 3C WT XX: embryonic day 16.5 (more )
Note: Double labeled: green - Sycp1 and Sycp3; red - Pecam1 (assay MGI:5528681).
Structure Level Pattern Image Note
TS24: oocyte Present 3C WT XX

Specimen 3C Fst-/- XX: embryonic day 16.5; Fsttm1Zuk/Fsttm1Zuk (more )
Note: Double labeled: green - Sycp1 and Sycp3; red - Pecam1 (assay MGI:5528681).
Structure Level Pattern Image Note
TS24: oocyte Present 3C Fst-/- XX The number of positive germ cells and the chromosomal localization of staining were normal in the mutant.

Specimen 3C Wnt4-/- XX: embryonic day 16.5; Wnt4tm1Amc/Wnt4tm1Amc (more )
Note: Double labeled: green - Sycp1 and Sycp3; red - Pecam1 (assay MGI:5528681).
Structure Level Pattern Image Note
TS24: germ cell of ovary Present 3C Wnt4-/- XX The number of positive germ cells and the chromosomal localization of staining were normal in the mutant.

Specimen 4B WT XX: embryonic day 18.5 (more )
Note: Double labeled: green - Sycp1 and Sycp3; red - Pecam1 (assay MGI:5528681).
Structure Level Pattern Image Note
TS26: oocyte Present Regionally restricted 4B WT XX Expression was detected in meiotic germ cells located in the coelomic domain.

Specimen 4B Fst-/- XX: embryonic day 18.5; Fsttm1Zuk/Fsttm1Zuk (more )
Note: Double labeled: green - Sycp1 and Sycp3; red - Pecam1 (assay MGI:5528681).
Structure Level Pattern Image Note
TS26: oocyte Present Single cells 4B Fst-/- XX More than 99% of meiotic germ cells were lost in the mutant, and the few remaining are enclosed in cord-like structures in the cortical region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory