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Gene Expression Data
Assay Details
Assay
Reference: J:161095 Hostikka SL, et al., Axial and appendicular skeletal transformations, ligament alterations, and motor neuron loss in Hoxc10 mutants. Int J Biol Sci. 2009;5(5):397-410
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5524983
Gene symbol: Hoxc10
Gene name: homeobox C10
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 13.5; Hoxc10tm1Emca/Hoxc10+ (more )
Structure Level Pattern Image Note
TS21: embryo Present Regionally restricted 2A Expression is in the posterior region of the embryo.
TS21: hindlimb Present Regionally restricted 2A Expression is in the proximal hindlimb.
Specimen 2B: embryonic day 13.5; Hoxc10tm1Emca/Hoxc10+ (more )
Structure Level Pattern Image Note
TS21: genital tubercle Present 2B
TS21: metanephros Present 2B
TS21: spinal cord Present 2B
TS21: vertebral cartilage condensation Present Regionally restricted 2B Expression is in the caudal prevertebrae.
Specimen 2C: embryonic day 13.5; Hoxc10tm1Emca/Hoxc10+ (more )
Structure Level Pattern Image Note
TS21: femur cartilage condensation Present Regionally restricted 2C Expression is in the perichondrium surrounding the cartilage condensations.
TS21: tibia-fibula pre-cartilage condensation Present Regionally restricted 2C Expression is in the perichondrium surrounding the cartilage condensations.
Specimen 2D: embryonic day 13.5; Hoxc10tm1Emca/Hoxc10+ (more )
Note: Double labeled: blue - Hoxc10 reporter; brown - Nefm (assay MGI:5524986).
Structure Level Pattern Image Note
TS21: femur cartilage condensation Present Regionally restricted 2D Expression is in the developing iliofemoral ligament attaching to the femur.
Specimen 2E,F: postnatal newborn; Hoxc10tm1Emca/Hoxc10+ (more )
Structure Level Pattern Image Note
TS27: ligament Present Regionally restricted 2E , 2F Expression is in the iliofemoral ligament.
Specimen 2G: postnatal newborn; Hoxc10tm1Emca/Hoxc10+ (more )
Note: Double labeled: blue - Hoxc10 reporter; brown - Isl1 (assay MGI:5524985).
Structure Level Pattern Image Note
TS27: spinal cord Present Regionally restricted 2G Expression is in the lumbar spinal cord.
Specimen 2H: postnatal newborn; Hoxc10tm1Emca/Hoxc10+ (more )
Note: Double labeled: blue - Hoxc10 reporter; brown - Isl1 (assay MGI:5524985).
Structure Level Pattern Image Note
TS27: spinal cord Present Regionally restricted 2H Expression is in the lumbar spinal cord.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory