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Gene Expression Data
Assay Details
Assay
Reference: J:91339 Takebayashi S, et al., Expression of beta-catenin in developing auditory epithelia of mice. Acta Otolaryngol Suppl. 2004;(551):18-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5478595
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: Anti-Beta-catenin
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 1A: embryonic day 12.0 (more )
Note: Double labeled: green - Ctnnb1; red - Mki67 (assay MGI:5478594).
Structure Level Pattern Image Note
TS20: cochlear duct epithelium Strong Regionally restricted 1A Intense expression was detected in the apical surface of the auditory epithelia. There was no difference in expression patterns observed among epithelial regions.

Specimen 1B: embryonic day 13.0 (more )
Note: Double labeled: green - Ctnnb1; red - Mki67 (assay MGI:5478594).
Structure Level Pattern Image Note
TS21: cochlear duct epithelium Present Regionally restricted 1B Expression was detected in the apical surface of all epithelial cells. In the immature organ of Corti cells expression was only in the apical surface. Expression that overlapped with Ki-67 was found both in the apical and basal portion.

Specimen 1C: embryonic day 15.0 (more )
Note: Double labeled: green - Ctnnb1; red - Mki67 (assay MGI:5478594).
Structure Level Pattern Image Note
TS23: cochlea epithelium Present Regionally restricted 1C Expression was limited to the apical surface of epithelial cells. Only weak expression was in the basal portion of the auditory epithelium. Weak expression was also noted in the organ of Corti.

Specimen 2A: embryonic day 17.0 (more )
Note: Double labeled: green - Ctnnb1; red - Myo7a (assay MGI:5478596).
Structure Level Pattern Image Note
TS25: organ of Corti Strong Regionally restricted 2A Expression was strong in the apical portion of the outer hair cells.
TS25: greater epithelial ridge Strong Regionally restricted 2A Expression was strong in the apical portion.
TS25: cochlea epithelium Weak Regionally restricted 2A Weak expression was detected in the apical portion between the outer hair cells and the greater epithelial ridge.

Specimen 2B: postnatal day 7 (more )
Note: Double labeled: green - Ctnnb1; red - Myo7a (assay MGI:5478596).
Structure Level Pattern Image Note
TS28: cochlea Strong Regionally restricted 2B Strong expression was detected in the apical portion of the outer hair cells and greater epithelial ridge, but not inner hair cells. Outer hair cell distribution corresponded to the location of adherens junctions. Expression was in pillar cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory