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Gene Expression Data
Assay Details
Assay
Reference: J:105951 McLaughlin D, et al., Expression pattern of the maternally imprinted gene Gtl2 in the forebrain during embryonic development and adulthood. Gene Expr Patterns. 2006 Apr;6(4):394-9
Assay type: RNA in situ
MGI Accession ID: MGI:5427475
Gene symbol: Meg3
Gene name: maternally expressed 3
Probe: clone c10.5/c7E/H1.9
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forebrain Strong Regionally restricted 1A Expression is in the basal forebrain at a ditsance from the ventricular zones.
TS20: neocortex Absent 1A
Specimen 1B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 1B Expression is in a continuous domain to extend from the lateral aspect of the ventral telencephalon into the dorsal and medial telencephalon.
Specimen 1C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 1C Expression is in a continuous domain to extend from the lateral aspect of the ventral telencephalon into the dorsal and medial telencephalon.
Specimen 1D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 1D Expression is in a continuous domain to extend from the lateral aspect of the ventral telencephalon into the dorsal and medial telencephalon.
Specimen 1E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: neocortex Present 1E Expression is throughout the rostro-caudal length of the neocortex.
TS24: thalamus Strong 1E Expression is in the thalamus and dorsal thalamus.
TS24: hippocampus Strong 1E
TS24: hypothalamus Strong 1E
Specimen 1F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: neocortex Present 1F Expression is throughout the rostro-caudal length of the neocortex.
TS24: thalamus Strong 1F Expression is in the thalamus and dorsal thalamus.
TS24: hippocampus Strong 1F
TS24: hypothalamus Strong 1F
Specimen 1G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: neocortex Present 1G Expression is throughout the rostro-caudal length of the neocortex.
TS24: thalamus Strong 1G Expression is in the thalamus and dorsal thalamus.
TS24: hippocampus Strong 1G
TS24: hypothalamus Strong 1G
Specimen 1H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: amygdala Strong 1H
TS27: dorsal thalamus Strong 1H
TS27: forebrain Strong 1H
TS27: hippocampus Strong 1H
TS27: hypothalamus Strong 1H
TS27: main olfactory bulb Strong 1H
Specimen 1I: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: amygdala Strong 1I
TS27: dorsal thalamus Strong 1I
TS27: hippocampus Strong 1I
TS27: hypothalamus Strong 1I
TS27: main olfactory bulb Strong 1I
TS27: thalamus Strong 1I
Specimen 1J: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: amygdala Strong 1J
TS27: dorsal thalamus Strong 1J
TS27: hippocampus Strong 1J
TS27: hypothalamus Strong 1J
TS27: main olfactory bulb Strong 1J
TS27: thalamus Strong 1J
Specimen 1K: postnatal adult (more )
Structure Level Pattern Image Note
TS28: forebrain Present 1K
TS28: hippocampus Present 1K
TS28: hypothalamus Present 1K
TS28: thalamus Present 1K
Specimen Not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Present
TS28: medulla oblongata Present
TS28: spinal cord Present
Specimen 2A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Present 2A
Specimen 2B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Present 2B
TS24: cortical plate Present 2B
Specimen 2C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical layer IV Strong 2C
TS27: cortical layer V Strong 2C
TS27: cortical layer II Present 2C
TS27: cortical layer III Present 2C
TS27: cortical layer VI Present 2C
TS27: cortical layer I Absent 2C
Specimen 2D: postnatal day 7 (more )
Note: Also stained for Rbfox3 (NeuN; assay MGI:5427485).
Structure Level Pattern Image Note
TS28: cortical layer I Present 2D
TS28: cortical layer II Present 2D
TS28: cortical layer III Present 2D
TS28: cortical layer IV Present 2D
TS28: cortical layer V Present 2D
TS28: cortical layer VI Present 2D
Specimen 2F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Weak Uniform 2F
TS28: cortical layer III Weak Uniform 2F
TS28: cortical layer IV Weak Uniform 2F
TS28: cortical layer V Weak Uniform 2F
TS28: cortical layer VI Weak Uniform 2F
Specimen 3A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Present 3A
Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Present 3B
Specimen 4A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Strong Regionally restricted 4A Expression is in the pyramidal cell layer.
TS24: corpus striatum Present Regionally restricted 4A Expression is in the dentate gyrus.
Specimen 4B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: hippocampus pyramidal cell layer Strong 4B
TS27: dentate gyrus Present 4B
Specimen 4C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Strong 4C
TS28: dentate gyrus Present 4C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory