About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:179032 Sharlin DS, et al., Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea. Endocrinology. 2011 Dec;152(12):5053-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5311189
Gene symbol: Slc7a5
Gene name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Antibody: anti-LAT1 (Q20)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3B: postnatal day 7 (more )
Note: Double labeled: red - Slc7a5; green - Pecam1 (assay MGI:5311190).
Structure Level Pattern Image Note
TS28: blood vessel Present Regionally restricted 3B Lat1 , 3B Lat1 CD31 DAPI , 3B Lat1 CD31 Protein almost exclusively localized to CD31-positive blood vessels in the spiral ligament and stria vascularis.

Specimen 3D: postnatal day 3 (more )
Note: Double labeled: red - Slc7a5; green - Myo7a (assay MGI:5311371).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 3D Signal localized to the cell membrane of hair cells and Deiters cells.
TS27: cochlear duct Present Regionally restricted 3D Positive in spiral vessel.

Specimen 3F: postnatal day 1 (more )
Note: Double labeled: red - Slc7a5; green - Pecam1 (assay MGI:5311190).
Structure Level Pattern Image Note
TS27: cochlear ganglion Weak Regionally restricted 3F Weak signal was detected in neuronal soma.
TS27: blood vessel Present 3F Signal was detected in CD31-positive blood vessels.

Specimen 3H: postnatal day 7 (more )
Note: Double labeled: red - Slc7a5; green - Pecam1 (assay MGI:5311190).
Structure Level Pattern Image Note
TS28: spiral vessel Present 3H Lat1 , 3H Lat1 CD31 DAPI , 3H Lat1 CD31 Signal overlapped with CD31.

Specimen S1B: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: spiral vessel Present S1B anti-Lat1


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory