About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:166449 Nishino J, et al., Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci. 2010 Nov 10;30(45):15228-40
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5300950
Gene symbol: Lgi4
Gene name: leucine-rich repeat LGI family, member 4
Reporter: lacZ
Antibody: anti-B-galactosidase
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A Glia: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Sections through the gut. Double labeled: green - Lgi4 reporter; red - Fabp7 (BFABP; assay MGI:5300955).
Structure Level Pattern Image Note
TS28: myenteric nerve plexus Present Regionally restricted 2A mut Glia LacZ , 2A mut Glia Merged Expressed in glial cells.
Specimen 2A Neuron: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Sections through the gut. Double labeled: green - Lgi4 reporter; red - Elavl3 (assay MGI:5300958) and Elavl4 (assay MGI:5300960).
Structure Level Pattern Image Note
TS28: myenteric nerve plexus Present Regionally restricted 2A mut Neuron Merged , 2A mut Neuron LacZ Expressed in glial cells, not neurons.
Specimen 2B Glia: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Double labeled: green - Lgi4 reporter; red - Fabp7 (BFABP; assay MGI:5300955).
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Regionally restricted 2B mut Glia LacZ , 2B mut Glia Merged Expressed in glial cells.
Specimen 2B Neuron: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Double labeled: green - Lgi4 reporter; red - Rbfox3 (assay MGI:5300959).
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present Regionally restricted 2B mut Neuron LacZ , 2B mut Neuron Merged Expressed in glial cells, not neurons.
Specimen 2C Glia: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Double labeled: green - Lgi4 reporter; red - Fabp7 (BFABP; assay MGI:5300955).
Structure Level Pattern Image Note
TS28: superior cervical ganglion Present Regionally restricted 2C mut Glia Merged , 2C mut Glia LacZ Expressed in glial cells.
Specimen 2C Neuron: postnatal adult; Lgi4tm1Sjm/Lgi4+ (more )
Note: Double labeled: green - Lgi4 reporter; red - Rbfox3 (assay MGI:5300959).
Structure Level Pattern Image Note
TS28: superior cervical ganglion Present Regionally restricted 2C mut Neuron Merged , 2C mut Neuron LacZ Expressed in glial cells, not neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory