About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:148991 Barkic M, et al., The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival. Mol Cell Biol. 2009 May;29(10):2489-504
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5295632
Gene symbol: Trp53
Gene name: transformation related protein 53
Antibody: Anti-p53
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 6I p53 wt: embryonic day 10.5 (more )
Note: Double labeled: red - Trp53; green - Bax (assay MGI:5295631).
Structure Level Pattern Image Note
TS17: neural tube Absent 6I merge wt (right) , 6I p53 wt
Specimen 6I p53 L24 Bst/+: embryonic day 10.5; Rpl24Bst/Rpl24+ (more )
Note: Double labeled: red - Trp53; green - Bax (assay MGI:5295631).
Structure Level Pattern Image Note
TS17: neural tube Present 6I merge L24 Bst/+ (right) , 6I p53 L24 Bst/+
Specimen 6J p53 wt: embryonic day 10.5 (more )
Note: Double labeled: red - Trp53; green - Npm1 (assay MGI:5295633).
Structure Level Pattern Image Note
TS17: neural tube Absent 6J p53 wt , 6J merge wt
Specimen 6J p53 L24 Bst/+: embryonic day 10.5; Rpl24Bst/Rpl24+ (more )
Note: Double labeled: red - Trp53; green - Npm1 (assay MGI:5295633).
Structure Level Pattern Image Note
TS17: neural tube Present 6J p53 L24 Bst/+ , 6J merge L24 Bst/+ Expression was largely in the cytoplasm of cells in the trunk neural tube. A very small portion of staining was present in the nucleus and some of it colocalizes with the nucleolar marker Npm1 (B23).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory