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Gene Expression Data
Assay Details
Assay
Reference: J:31131 Pfaff SL, et al., Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Cell. 1996 Jan 26;84(2):309-20
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5294909
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Results
Specimen 5A +/-: embryonic day 9.5; Isl1tm1Tmj/Isl1+ (more )
Note: This is a 25-somite stage embryo. Double labeled: green - Tubb3; red - Foxa2 (assay MGI:4359917).
Structure Level Pattern Image Note
TS15: neural tube Present Non-Uniform 5A The location of the expression suggests that most expressing cells are motor neurons.
Specimen 5B -/-: embryonic day 9.5; Isl1tm1Tmj/Isl1tm1Tmj (more )
Note: This is a 25-somite stage embryo. Double labeled: green - Tubb3; red - Foxa2 (assay MGI:4359917).
Structure Level Pattern Image Note
TS15: neural tube Present Non-Uniform 5B Expression levels are depleted relative to those seen in heterozygotes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory