Nav2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:147809 Masuda T, et al., Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord. Brain Res. 2009 Jan 16;1249:61-7
Assay type:	RNA in situ
MGI Accession ID:	MGI:3844029
Gene symbol:	Nav2
Gene name:	neuron navigator 2

Probe:	Nav2 probe1
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen Table 1: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: future spinal cord	Strong	Regionally restricted		Expression was high in the dorsal spinal cord.

Specimen 3C left: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: future spinal cord	Present	Regionally restricted	3C ISH	Expression was detected in the dorsolateral part of the spinal cord including the dorsal root entry zone. Expression was also noted in a subpopulation of motor neurons.
TS17: neural tube roof plate	Absent		3C ISH
TS17: dorsal root ganglion	Present	Regionally restricted	3C ISH	Expression was detected in dorsal root ganglion neurons.
TS17: dermomyotome	Present		3C ISH

Specimen 3C right: embryonic day 10.5 (more

)
Note: Double labeled: blue - Nav2; brown - Isl1 (assay MGI:3844024) and Is12 (assay MGI:3844025).

Structure	Level	Pattern	Image	Note
TS17: future spinal cord	Present	Regionally restricted	3C ISH Islet-1/2	Expression was detected in the dorsolateral part of the spinal cord including the dorsal root entry zone. Expression was also noted in a subpopulation of motor neurons.
TS17: neural tube roof plate	Absent		3C ISH Islet-1/2
TS17: dorsal root ganglion	Present	Regionally restricted	3C ISH Islet-1/2	Expression was detected in dorsal root ganglion neurons.
TS17: dermomyotome	Present		3C ISH Islet-1/2

Specimen 4C left: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: spinal cord ventricular layer	Strong	Widespread	4C ISH	Expression was strong throughout the ventricular zone.
TS20: spinal cord	Present	Widespread	4C ISH	Expression was detected in the whole spinal cord.
TS20: dorsal root ganglion	Present	Regionally restricted	4C ISH	Expression was detected in dorsal root ganglion neurons.

Specimen 4C right: embryonic day 12.5 (more

)
Note: Double labeled: blue - Nav2; brown - Isl1 (assay MGI:3844024) and Is12 (assay MGI:3844025).

Structure	Level	Pattern	Image	Note
TS20: spinal cord ventricular layer	Strong	Widespread	4C ISH Islet-1/2	Expression was strong throughout the ventricular zone.
TS20: spinal cord	Present	Widespread	4C ISH Islet-1/2	Expression was detected in the whole spinal cord.
TS20: dorsal root ganglion	Present	Regionally restricted	4C ISH Islet-1/2	Expression was detected in dorsal root ganglion neurons.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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