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Gene Expression Data
Assay Details
Assay
Reference: J:139974 Sakae N, et al., Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants. Hum Mol Genet. 2008 Oct 15;17(20):3191-203
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3812211
Gene symbol: Gad1
Gene name: glutamate decarboxylase 1
Antibody: anti-GAD67
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1C WT: postnatal week 12-15 (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present Regionally restricted 1C WT merge , 1C GAD67 WT Expression is present in axon bundles that form the mossy fiber pathway.
TS28: hippocampus CA3 Present Regionally restricted 1C WT merge , 1D WT , 1C GAD67 WT Expression is present in axon bundles that form the mossy fiber pathway.
Specimen 1C KO: postnatal week 12-15; Fez1tm1Kei/Fez1tm1Kei (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present Regionally restricted 1C KO merge , 1C GAD67 KO Expression is present axon bundles that form the mossy fiber pathway.
TS28: hippocampus CA3 Present Regionally restricted 1C GAD67 KO , 1C KO merge , 1D KO Expression is present axon bundles that form the mossy fiber pathway.
Specimen 1E WT: postnatal week 12-15 (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 1E WT merge , 1E GAD67 WT Expression is present in GABA-ergic inhibitory neurons.
Specimen 1E KO: postnatal week 12-15; Fez1tm1Kei/Fez1tm1Kei (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 1E KO merge , 1E GAD67 KO Expression is present in GABA-ergic inhibitory neurons.
Specimen 1F WT: postnatal week 12-15 (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: cortical layer II Present Regionally restricted 1F GAD67 WT , 1F WT merge Expression is present in GABA-ergic inhibitory neurons.
TS28: cortical layer III Present Regionally restricted 1F GAD67 WT , 1F WT merge Expression is present in GABA-ergic inhibitory neurons.
Specimen 1F KO: postnatal week 12-15; Fez1tm1Kei/Fez1tm1Kei (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: cortical layer II Present Regionally restricted 1F GAD67 KO , 1F KO merge Expression is present in GABA-ergic inhibitory neurons.
TS28: cortical layer III Present Regionally restricted 1F GAD67 KO , 1F KO merge Expression is present in GABA-ergic inhibitory neurons.
Specimen 1G WT: postnatal week 12-15 (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: caudate-putamen Present Regionally restricted 1G WT merge , 1G GAD67 WT Expression is present in GABA-ergic inhibitory neurons.
Specimen 1G KO: postnatal week 12-15; Fez1tm1Kei/Fez1tm1Kei (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: caudate-putamen Present Regionally restricted 1G GAD67 KO , 1G KO merge Expression is present in GABA-ergic inhibitory neurons.
Specimen 1H WT: postnatal week 12-15 (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: accumbens nucleus Present Regionally restricted 1H WT merge , 1H GAD67 WT Expression is present in GABA-ergic inhibitory neurons.
Specimen 1H KO: postnatal week 12-15; Fez1tm1Kei/Fez1tm1Kei (more )
Note: Double labeled: green - Gad1; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: accumbens nucleus Present Regionally restricted 1H KO merge , 1H GAD67 KO Expression is present in GABA-ergic inhibitory neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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