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Gene Expression Data
Assay Details
Assay
Reference: J:139974 Sakae N, et al., Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants. Hum Mol Genet. 2008 Oct 15;17(20):3191-203
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3812199
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Cy5
Results
Specimen 1I WT upper: postnatal week 12-15 (more )
Note: Double labeled: blue - Th; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present Regionally restricted 1I TH WT (upper) , 1I WT merge (upper) Expression is present in the somata of dopaminergic neurons.
Specimen 1I WT lower: postnatal week 12-15 (more )
Note: Double labeled: blue - Th; red - Fez1 (assay MGI:3812194).
Structure Level Pattern Image Note
TS28: accumbens nucleus Present Regionally restricted 1I WT merge (lower) , 1I TH WT (lower) Expression is present in dopaminergic axon fibers projecting to the nucleus accumbens.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory