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Phenotypes Associated with This Genotype
Genotype
MGI:3653864
Allelic
Composition		 Chgatm1Gnh/Chgatm1Gnh
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chgatm1Gnh mutation (3 available); any Chga mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal urine catecholamine level ( J:111025 )
• elevated urine levels of epinephrine, norepinephrine, and dopamine
• however; renal and hepatic function are similar to wild-type

endocrine/exocrine glands
endocrine/exocrine gland phenotype ( J:111025 )
N
• gross adrenal gland morphology and microscopic structure of epinephrine and norepinephrine storing cells are similar to wild-type
• endocrine gland function and secretory function of the sympathetic nervous system, somatotrophs, and gonadotrophs are not different from wild-type

reproductive system
reproductive system phenotype ( J:111025 )
N
• males and females are fertile and produce normal sized litters

homeostasis/metabolism
abnormal urine catecholamine level ( J:111025 )
• elevated urine levels of epinephrine, norepinephrine, and dopamine
• however; renal and hepatic function are similar to wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory