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Gene Expression Data
Assay Details
Assay
Reference: J:106710 Takemoto M, et al., Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J. 2006 Mar 8;25(5):1160-74
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3625988
Gene symbol: Pdgfrb
Gene name: platelet derived growth factor receptor, beta polypeptide
Antibody: anti-mouse Pdgfrb (APB5; #14-1402-82)
Detection system: Secondary antibody
Results
Specimen 5A +/+: embryonic day 18.5 (more )
Note: Double labeled: green - Pdgfrb; red - Nphs1 (assay MGI:3625987).
Structure Level Pattern Image Note
TS26: presumptive mesangium of capillary loop renal corpuscle Present Regionally restricted 5A Nphs1/Pdgfrb +/+ Expression is in mesangial cells.

Specimen 5A -/-: embryonic day 18.5; Foxc2tm1Miu/Foxc2tm1Miu (more )
Note: Double labeled: green - Pdgfrb; red - Nphs1 (assay MGI:3625987).
Structure Level Pattern Image Note
TS26: presumptive mesangium of capillary loop renal corpuscle Present Regionally restricted 5A Nphs1/Pdgfrb -/- Expression is in mesangial cells but the distribution is abnormal in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory