Analysis Tools
mortality/aging
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• all dead within 4-6 hours of delivery
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limbs/digits/tail
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• abnormal in the hindlimbs but not forelimbs
• smaller cells and less densely packed
|
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• in less extreme cases, all five digits are present but are abnormal
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monodactyly
(
J:101729
)
|
• on the hind limb
• occurs in more extreme cases
|
|
• malformed in contrast to forelimbs which are normal
|
|
• in extreme cases, tibia is absent
• femur is always normal
|
embryo
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• abnormal in the hindlimbs but not forelimbs
• smaller cells and less densely packed
|
homeostasis/metabolism
|
• epidermis is more permeable
• fetus shows 7 fold greater trans-epidermal water loss
• 5-10% of body weight lost within 4-6 hours of delivery
|
integument
|
• epidermis is more permeable
• fetus shows 7 fold greater trans-epidermal water loss
• 5-10% of body weight lost within 4-6 hours of delivery
|
|
• dorsal and ventral skin folds broader and more disorganized
|
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• 4-6 layers as usual but flatter cells than normal
• vesicles rather than lipid discs between stratum granulosum and corneum
• lamellar membranes in corneum were disorganized and highly variable in thickness
• 5 fold fewer corneodesmosomes
• lower layers of epidermis essentially normal
|
shiny skin
(
J:101729
)
|
• red and glossy immediately after caesarian delivery
• sticky to touch
|
