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Gene Expression Data
Assay Details
Assay
Reference: J:76815 Broccoli V, et al., Dmbx1 is a paired-box containing gene specifically expressed in the caudal most brain structures. Mech Dev. 2002 Jun;114(1-2):219
Assay type: RNA in situ
MGI Accession ID: MGI:3039779
Gene symbol: Dmbx1
Gene name: diencephalon/mesencephalon homeobox 1
Results
Specimen 2A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: 1st branchial arch Present 2A
TS13: future brain Present Regionally restricted 2A Expression is in the anterior neural plate.

Specimen 2C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future brain Present Regionally restricted 2C Expression is in the anterior neural plate with the anterior border extending over part of the diencephalic anlage.
TS13: future midbrain Present Regionally restricted 2C Expression is in the anterior neural plate with the anterior border extending over part of the diencephalic anlage.
TS13: future prosencephalon Present Regionally restricted 2C Expression is in the anterior neural plate with the anterior border extending over part of the diencephalic anlage.

Specimen 2E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: diencephalon Present Regionally restricted 2E Expression is in prosomere 1.
TS15: future midbrain Present Regionally restricted 2E The caudal limit of expression is at the caudal midbrain border, and expression is absent at the isthmus.
TS15: future hindbrain Absent 2E

Specimen 2I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Strong Regionally restricted 2I Expression is in a bilateral stream of cells in the rhombic lip.

Specimen 2J, K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: olfactory epithelium Present 2J , 2K
TS17: midbrain Present 2K , 2J
TS17: midbrain roof plate Absent 2J , 2K

Specimen 2L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: olfactory epithelium Strong 2L
TS20: cerebellum primordium Strong Regionally restricted 2L Expression is in a bilateral stream of cells.

Specimen 2M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 2M
TS20: forebrain Present Regionally restricted 2M Expression is maintained in the alar plate and is absent in the basal plate and extends from the caudal mesencephalon to prosomere 1.
TS20: midbrain Present Regionally restricted 2M Expression is maintained in the alar plate and is absent in the basal plate and extends from the caudal mesencephalon to prosomere 1.

Specimen 2N: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain Present 2N
TS20: spinal cord Present 2N

Specimen 2O: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebellum Present Regionally restricted 2O Expressing cells disperse rostrally over the surface of the cerebellar anlage.
TS22: forebrain Present Regionally restricted 2O Expression is maintained in the alar plate and is absent in the basal plate and extends from the caudal mesencephalon to prosomere 1.
TS22: midbrain Present Regionally restricted 2O Expression is maintained in the alar plate and is absent in the basal plate and extends from the caudal mesencephalon to prosomere 1.
TS22: midbrain tegmentum Absent 2O
TS22: pons Absent 2O

Specimen 2P: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebellum Present Regionally restricted 2P Expressing cells disperse rostrally over the surface of the cerebellar anlage.
TS22: midbrain Present Regionally restricted 2P Expression is in the alar plate.
TS22: midbrain tegmentum Absent 2P
TS22: pons Absent 2P

Specimen Not Shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forebrain Present
TS24: midbrain Present

Specimen 3A: embryonic day 11.5 (more )
Note: Also stained for Pax7 (assay MGI:3039938).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Regionally restricted 3A Expression is in a domain below the sulcus limitans and does not overlap with that of Pax7.

Specimen 3C: embryonic day 11.5 (more )
Note: Also stained for En1 (assay MGI:3039791).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Regionally restricted 3C Expression is in a domain below the sulcus limitans of V0 interneurons abutting En1 expressing cells.

Specimen 3D: embryonic day 11.5 (more )
Note: Also stained for Pax6 (assay MGI:3039932).
Structure Level Pattern Image Note
TS19: neural tube lateral wall Present Regionally restricted 3D Expression is in a domain below the sulcus limitans and does not overlap with that of Pax6.

Specimen 3E: embryonic day 12.5 (more )
Note: Also stained for Pax7 (assay MGI:3039938).
Structure Level Pattern Image Note
TS20: spinal cord lateral wall Present Regionally restricted 3E Expression is in a domain below the sulcus limitans and does not overlap with that of Pax7.

Specimen 3G: embryonic day 12.5 (more )
Note: Also stained for En1 (assay MGI:3039791).
Structure Level Pattern Image Note
TS20: spinal cord lateral wall Present Regionally restricted 3G Expression is in a domain below the sulcus limitans.

Specimen 3I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 3I
TS20: midbrain Present 3I
TS20: midbrain roof plate Present 3I

Specimen 3K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord lateral wall Present Regionally restricted 3K Expression is in a domain below the sulcus limitans in the differentiated V0 interneurons.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory