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Gene Expression Data
Assay Details
Assay
Reference: J:84360 Dalvin S, et al., Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung. Gene Expr Patterns. 2003 Jun;3(3):279-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2670869
Gene symbol: Unc5b
Gene name: unc-5 netrin receptor B
Antibody: Unch52 antibody
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3I,J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung epithelium Present 3I , 3J Expression is at the basal and apical surfaces.
TS20: lung mesenchyme Absent 3J , 3I

Specimen 3K,L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present 3K , 3L Expression is at the basal and apical surfaces.
TS22: lung mesenchyme Absent 3L , 3K

Specimen 3M,N: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung epithelium Present 3M , 3N Expression is at the apical side of the bronchiolar epithelium.
TS24: lung mesenchyme Absent 3M , 3N

Specimen 3O,P: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Present 3O , 3P Expression is at the apical side of the bronchiolar epithelium.
TS26: lung mesenchyme Absent 3P , 3O

Specimen 4A,B,C: embryonic day 12.5 (more )
Note: Double labeled: red - Unc5b; green - Dcc (assay MGI:2670868).
Structure Level Pattern Image Note
TS20: lung epithelium Present 4B , 4A , 4C Expression on the basal and lumenal surfaces overlaps with that of Dcc.

Specimen 4D,E,F: embryonic day 14.5 (more )
Note: Double labeled: red - Unc5b; green - Dcc (assay MGI:2670868).
Structure Level Pattern Image Note
TS22: lung epithelium Present 4F , 4D , 4E Expression is on the lumenal surfaces and overlaps with that of Dcc.

Specimen 4G,H,I: embryonic day 16.5 (more )
Note: Double labeled: red - Unc5b; green - Dcc (assay MGI:2670868).
Structure Level Pattern Image Note
TS24: lung epithelium Present Single cells 4H , 4G , 4I Few epithelial cells express both Dcc and Unc5h2.

Specimen 4J,K,L: embryonic day 18.5 (more )
Note: Double labeled: red - Unc5b; green - Dcc (assay MGI:2670868).
Structure Level Pattern Image Note
TS26: lung epithelium Present Single cells 4J , 4K , 4L Few epithelial cells express both Dcc and Unc5h2.

Specimen Not Shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: liver Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory