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Gene Expression Data
Assay Details
Assay
Reference: J:63189 Lammert E, et al., Notch gene expression during pancreatic organogenesis. Mech Dev. 2000 Jun;94(1-2):199-203
Assay type: RNA in situ
MGI Accession ID: MGI:2385767
Gene symbol: Notch1
Gene name: notch 1
Probe: Notch1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 9.5 (more )
Note: Double labeled: blue/violet - Notch1; brown - Gcg (assay MGI:2385763).
Structure Level Pattern Image Note
TS15: pancreas primordium Present 1A In the dorsal pancreatic bud. Expression does not overlap with that of glucagon.
Specimen 1D: embryonic day 10.5 (more )
Note: Double labeled: blue/violet - Notch1; brown - Gcg (assay MGI:2385763).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted 1D Expression in dorsal pancreatic bud epithelium, not mesenchyme. There was no Notch1 expression in Glucagon expressing cells.
Specimen 1E: embryonic day 10.5 (more )
Note: Double labeled: blue/violet - Notch1; brown - Gcg (assay MGI:2385763).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted 1E Expression in ventral pancreatic bud epithelium, not mesenchyme.
Specimen 2A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted 2A Uniform expressison in the dorsal pancreas. Broad expression in the epithelium including the acini, and in some endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory