B6;SJL-Apoe<tm1.1(APOE*4)Adiuj> Plcg2<em1Msasn> Trem2<em1Adiuj>/J Strain Detail MGI Mouse MGI:6316323

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B6;SJL-Apoe^{tm1.1(APOE*4)Adiuj} Plcg2^em1Msasn Trem2^em1Adiuj/J Strain Detail

Summary

Strain Name

B6;SJL-Apoe^{tm1.1(APOE*4)Adiuj} Plcg2^em1Msasn Trem2^em1Adiuj/J
Attributes

endonuclease-mediated mutation, mutant strain, targeted mutation
MGI ID

MGI:6316323

Other IDs

JAX:030771

3 associated mutations

Mutation Carried	Marker
Apoe^{tm1.1(APOE*4)Adiuj}	Apoe
Plcg2^em1Msasn	Plcg2
Trem2^em1Adiuj	Trem2

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
JAX:030771	JAX	B6;SJL-Apoe^{tm1.1(APOE*4)Adiuj} Plcg2^em1Msasn Trem2^em1Adiuj/J	exact match to ID

Earliest

J:308279 Maguire E, et al., PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease-protective variant PLCgamma2 R522. EMBO J. 2021 Jul 13;:e105603
All

1

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