B6.Cg-Tg(CMV-cat,-ROCK2*)3-1Koba/KobaRbrc Strain Detail MGI Mouse MGI:6144615

B6.Cg-Tg(CMV-cat,-ROCK2*)3-1Koba/KobaRbrc Strain Detail

Summary

Strain Name

B6.Cg-Tg(CMV-cat,-ROCK2*)3-1Koba/KobaRbrc
Attributes

congenic, mutant strain, transgenic
MGI ID

MGI:6144615
Synonyms

B6.Cg-Tg(CAT-Rho-K DN)3-1Koba/KobaRbrc

Other IDs

RBRC01294

Description

Developed by Kazuto Kobayashi, Fukushima Medical University School of Medicine in 1998. The transgene containing CMV promoter and bovine Rho-K DN cDNA separated by a floxed chloramphenicol acetyltransferase (CAT) cassette was injected into the pronuclei of B6D2F2 fertilized eggs. The transgenic mice were backcrossed to C57BL/6JJcl.

1 associated mutation

Mutation Carried	Marker
Tg(CMV-cat,-ROCK2*)3-1Koba	Tg(CMV-cat,-ROCK2*)3-1Koba

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
RBRC01294	RBRC	B6.Cg-Tg(CAT-Rho-K DN)3-1Koba/KobaRbrc	exact match to ID

Earliest

J:100207 Kobayashi K, et al., Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci. 2004 Apr 7;24(14):3480-8
All

5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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