About   Help   FAQ
B6.129S7-Trp53tm1Brd/2Tac Strain Detail
Summary
  • Strain Name
    B6.129S7-Trp53tm1Brd/2Tac
  • Attributes
    congenic, mutant strain, targeted mutation
  • MGI ID
    MGI:4838440
  • Synonyms
    B6.129-Trp53tm1Brd N12, P53N12, TSG-p53(R)
  • Other IDs
    TAC:908, TAC:p53n12, TAC:P53N12
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Mutation Carried Marker
Trp53tm1Brd Trp53
Find Mice (IMSR)
1 associated strain record at IMSR
IMSR Repository IMSR Strain Why Matched
TAC:P53N12 TAC B6.129-Trp53tm1Brd N12 exact match to ID
References
  • Earliest
    J:175588 Burga LN, et al., Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice. Breast Cancer Res. 2011 Mar 11;13(2):R30
  • All
    4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory