Sequence Detail

ID/Version

W8DXL4 (UniProt | EBI)

Last sequence update: 2014-05-14
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 {ECO:0000305};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 681 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lrit3	leucine-rich repeat, immunoglobulin-like and transmembrane domains 3	19	98	4	6

Sequence references in MGI

J:214644 Neuille M, et al., Lrit3 deficient mouse (nob6): a novel model of complete congenital stationary night blindness (cCSNB). PLoS One. 2014;9(3):e90342
J:241495 Charette JR, et al., A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects. Adv Exp Med Biol. 2016;854:177-83
J:242812 Neuille M, et al., LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation. Eur J Neurosci. 2015 Aug;42(3):1966-75
J:257161 Neuille M, et al., LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells. Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1768-1778