Sequence Detail

ID/Version

Q9Z306 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Solute carrier family 22 member 4 {ECO:0000303|PubMed:15489334};AltName: Full=Organic cation/carnitine transporter 1 {ECO:0000303|PubMed:11010964}; Short=Octn1 {ECO:0000303|PubMed:11010964};

Provider

SWISS-PROT

Sequence

Polypeptide 553 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc22a4	solute carrier family 22 (organic cation transporter), member 4	65	105	4	9

Sequence references in MGI

J:66383 Tamai I, et al., Molecular and functional characterization of organic Cation/Carnitine transporter family in mice. J Biol Chem. 2000 Dec 22;275(51):40064-72
J:109656 Lamhonwah AM, et al., Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1315-25
J:114764 Gisler SM, et al., PDZK1: I. a major scaffolder in brush borders of proximal tubular cells. Kidney Int. 2003 Nov;64(5):1733-45
J:207006 Kato Y, et al., Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1. Pharm Res. 2010 May;27(5):832-40
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:336070 Tamai I, et al., Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations. Mol Pharm. 2004 Jan 12;1(1):57-66
J:336139 Sugiura T, et al., Functional expression of carnitine/organic cation transporter OCTN1/SLC22A4 in mouse small intestine and liver. Drug Metab Dispos. 2010 Oct;38(10):1665-72