Sequence Detail

ID/Version

Q9Z2Y3 Q9Z216 Q9Z0E9 Q8K4M8 Q8K3E1 (UniProt | EBI)

Last sequence update: 2003-11-28
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Homer protein homolog 1 {ECO:0000305}; Short=Homer-1;AltName: Full=VASP/Ena-related gene up-regulated during seizure and LTP 1; Short=Vesl-1 {ECO:0000303|Ref.4};

Provider

SWISS-PROT

Sequence

Polypeptide 366 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Homer1	homer scaffolding protein 1	78	101	3	13

Sequence references in MGI

J:50718 Xiao B, et al., Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron. 1998 Oct;21(4):707-16
J:78892 Saito H, et al., An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells. Biochem Biophys Res Commun. 2002 Aug 23;296(3):523-9
J:173402 Wang X, et al., Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. Hum Mol Genet. 2011 Aug 1;20(15):3093-108
J:201867 Han K, et al., SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature. 2013 Nov 7;503(7474):72-7
J:239710 Fossati M, et al., SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses. Neuron. 2016 Jul 20;91(2):356-69
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89