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Sequence Detail
ID/Version
Q9Z2R6 (UniProt | EBI) Last sequence update: 1999-05-01
Last annotation update: 2020-06-17
Sequence
description
from provider
RecName: Full=Protein unc-119 homolog A;AltName: Full=Retinal protein 4; Short=mRG4;
Provider SWISS-PROT
Sequence
Polypeptide 240 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Unc119 unc-119 lipid binding chaperone 31 73 9 5
Sequence references in MGI J:49983 Swanson DA, et al., Mammalian orthologs of C. elegans unc-119 highly expressed in photoreceptors. Invest Ophthalmol Vis Sci. 1998 Oct;39(11):2085-94
J:123195 Ishiba Y, et al., Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function. Exp Eye Res. 2007 Mar;84(3):473-85
J:136903 Haeseleer F, Interaction and colocalization of CaBP4 and Unc119 (MRG4) in photoreceptors. Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2366-75
J:174011 Zhang H, et al., UNC119 is required for G protein trafficking in sensory neurons. Nat Neurosci. 2011;14(7):874-80
J:207818 Karim Z, et al., UNC119 inhibits dynamin and dynamin-dependent endocytic processes. Cell Signal. 2010 Jan;22(1):128-37
J:282598 Chaya T, et al., Cul3-Klhl18 ubiquitin ligase modulates rod transducin translocation during light-dark adaptation. EMBO J. 2019 Dec 2;38(23):e101409

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory