Sequence Detail

ID/Version

Q9Z2E9 Q3TY41 Q3U1S5 Q810B0 Q9JJC2 Q9JMF1 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Seipin;AltName: Full=Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 383 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bscl2	BSCL2 lipid droplet biogenesis associated, seipin	28	100	4	19

Sequence references in MGI

J:50600 Downes GB, et al., Structure and mapping of the G protein gamma3 subunit gene and a divergently transcribed novel gene, gng3lg. Genomics. 1998 Oct 15;53(2):220-30
J:64911 Inoue S, et al., Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. Biochem Biophys Res Commun. 2000 Feb 16;268(2):553-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:173404 Cui X, et al., Seipin ablation in mice results in severe generalized lipodystrophy. Hum Mol Genet. 2011 Aug 1;20(15):3022-30
J:183701 Chen W, et al., Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation. Mol Cell Biol. 2012 Mar;32(6):1099-111
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89